Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 106608..107251 Replicon plasmid HDIAp1
Accession NZ_LT960615
Organism Hartmannibacter diazotrophicus strain E19T

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HDIA_RS25005 Protein ID WP_099559221.1
Coordinates 106608..106997 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HDIA_RS25010 Protein ID WP_099559222.1
Coordinates 106997..107251 (-) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HDIA_RS24975 102025..102999 + 975 WP_099559245.1 NAD(P)-binding domain-containing protein -
HDIA_RS25550 103204..103347 - 144 WP_162292712.1 hypothetical protein -
HDIA_RS24980 103543..103866 - 324 WP_099559217.1 hypothetical protein -
HDIA_RS24990 104879..105127 + 249 WP_099559218.1 plasmid stabilization protein -
HDIA_RS24995 105124..105537 + 414 WP_099559219.1 type II toxin-antitoxin system VapC family toxin -
HDIA_RS25000 105562..106611 - 1050 WP_099559220.1 site-specific integrase -
HDIA_RS25005 106608..106997 - 390 WP_099559221.1 type II toxin-antitoxin system VapC family toxin Toxin
HDIA_RS25010 106997..107251 - 255 WP_099559222.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
HDIA_RS25015 107534..108373 + 840 WP_099559223.1 DUF1403 family protein -
HDIA_RS25020 108407..111382 - 2976 WP_099559224.1 Tn3 family transposase -
HDIA_RS25025 111536..112120 + 585 WP_099559225.1 recombinase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..122332 122332


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-124)

Antitoxin

(1-83)


Sequences


Toxin        


Download         Length: 130 a.a.        Molecular weight: 14289.12 Da        Isoelectric Point: 5.1814

>T293859 WP_099559221.1 NZ_LT960615:c106997-106608 [Hartmannibacter diazotrophicus]
MVIDTSAIVAIFFNEPDAMTYRERIAADPIRLISAATLLEASMVIEGRFGEAGGAEFDLWLHKAEVEVVAVNHEHADQAR
RAWRRYGKGRHPASLNYGDCFSYALSSLSGEPLLFKGNDFKQTDIQAVS

Download         Length: 390 bp


Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9346.79 Da        Isoelectric Point: 4.8660

>AT293859 WP_099559222.1 NZ_LT960615:c107251-106997 [Hartmannibacter diazotrophicus]
MALSIKDPETEKLARALAVRTGETITVATRRALEERLRRIGLDAKKAALIEDMEAMQRRLSVLPVLDDRSADDIIGYDEN
GIPI

Download         Length: 255 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References