Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 1665047..1665694 Replicon chromosome
Accession NZ_LT960612
Organism Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag VTAP4600_RS24425 Protein ID WP_102525281.1
Coordinates 1665293..1665694 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag VTAP4600_RS24420 Protein ID WP_102524061.1
Coordinates 1665047..1665280 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VTAP4600_RS24405 1662073..1662954 - 882 WP_102525279.1 DoxX family protein -
VTAP4600_RS24410 1663001..1664188 - 1188 WP_102525280.1 MFS transporter -
VTAP4600_RS24415 1664293..1664577 - 285 WP_197708686.1 hypothetical protein -
VTAP4600_RS24420 1665047..1665280 + 234 WP_102524061.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
VTAP4600_RS24425 1665293..1665694 + 402 WP_102525281.1 type II toxin-antitoxin system VapC family toxin Toxin
VTAP4600_RS26110 1665712..1665813 + 102 Protein_1437 DNA mismatch repair protein MutT -
VTAP4600_RS24430 1666035..1666871 + 837 WP_102525282.1 AraC family transcriptional regulator -
VTAP4600_RS24435 1666942..1667724 + 783 WP_102525283.1 AzlC family ABC transporter permease -
VTAP4600_RS24440 1667724..1668035 + 312 WP_102525284.1 AzlD domain-containing protein -
VTAP4600_RS24445 1668227..1668742 + 516 WP_102525285.1 peptide deformylase -
VTAP4600_RS24450 1668818..1669138 - 321 WP_102525286.1 heavy metal-binding domain-containing protein -
VTAP4600_RS24455 1669355..1670098 + 744 WP_102525287.1 phosphatase -
VTAP4600_RS24460 1670151..1670534 - 384 WP_102525288.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14788.33 Da        Isoelectric Point: 7.8042

>T293853 WP_102525281.1 NZ_LT960612:1665293-1665694 [Vibrio tapetis subsp. tapetis]
MLDTCICSFIMREQPIAVLKMLQDVVGKQHRIVISAITYQEMQYGLLGKKASPKHAVLVAEFLKRVDEILPWDKVAVDAT
TEVKRSLMAKGTPIGNNDTAIAGHAIATGCVLVTNNTREFQRVEGLKLEDWVH

Download         Length: 402 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9043.07 Da        Isoelectric Point: 4.4453

>AT293853 WP_102524061.1 NZ_LT960612:1665047-1665280 [Vibrio tapetis subsp. tapetis]
MRTVSIFKNGKNQAVRLPKDFEFDGVNELEIHKEGDVITLRPARPDWLSFGEQEKPDEDFMANREDVIKDEGRFNFE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References