Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 1237784..1238580 Replicon chromosome
Accession NZ_LT960612
Organism Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag VTAP4600_RS22570 Protein ID WP_102524971.1
Coordinates 1238050..1238580 (+) Length 177 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID B1KM02
Locus tag VTAP4600_RS22565 Protein ID WP_005423939.1
Coordinates 1237784..1238053 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VTAP4600_RS22535 1233606..1234451 - 846 WP_102524969.1 lysophospholipase -
VTAP4600_RS22555 1235601..1236623 + 1023 WP_197708672.1 hypothetical protein -
VTAP4600_RS22560 1236623..1237552 + 930 WP_145958607.1 hypothetical protein -
VTAP4600_RS22565 1237784..1238053 + 270 WP_005423939.1 DUF1778 domain-containing protein Antitoxin
VTAP4600_RS22570 1238050..1238580 + 531 WP_102524971.1 GNAT family N-acetyltransferase Toxin
VTAP4600_RS22575 1238753..1240495 - 1743 WP_102524972.1 alpha-galactosidase -
VTAP4600_RS22580 1240812..1242677 + 1866 WP_102524973.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(96-168)

Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 19789.05 Da        Isoelectric Point: 9.3099

>T293852 WP_102524971.1 NZ_LT960612:1238050-1238580 [Vibrio tapetis subsp. tapetis]
VSYSKAFKELDKSQHDRASFDCGEKELNGFIQTQAAKHMQAGISRTMVLPASVPLPNQKYPICSFYSIAPSSISRDTLPK
AMAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIKALEYLWEINSHMRAYAIVVDCFTEQAESFYAKYGFEVLCEING
RARMFIPMKTVGQLFT

Download         Length: 531 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9807.19 Da        Isoelectric Point: 4.4290

>AT293852 WP_005423939.1 NZ_LT960612:1237784-1238053 [Vibrio tapetis subsp. tapetis]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVISEHESITVEANVFDQFMIACDEAKAPNKALLEAA
AFTKSGEFK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1B9PGK1

References