293851

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 618776..619542 Replicon chromosome
Accession NZ_LT960612
Organism Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag VTAP4600_RS19910 Protein ID WP_102524526.1
Coordinates 618776..619273 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag VTAP4600_RS19915 Protein ID WP_102524527.1
Coordinates 619270..619542 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VTAP4600_RS19900 615723..617252 - 1530 WP_102521342.1 transposase -
VTAP4600_RS19905 617788..618636 + 849 WP_102524525.1 hypothetical protein -
VTAP4600_RS19910 618776..619273 - 498 WP_102524526.1 GNAT family N-acetyltransferase Toxin
VTAP4600_RS19915 619270..619542 - 273 WP_102524527.1 DUF1778 domain-containing protein Antitoxin
VTAP4600_RS26005 619814..619990 + 177 WP_172443187.1 hypothetical protein -
VTAP4600_RS19925 619995..620399 - 405 WP_102524528.1 hypothetical protein -
VTAP4600_RS19930 620386..620622 - 237 WP_102524529.1 hypothetical protein -
VTAP4600_RS19935 620828..620998 + 171 Protein_540 type II toxin-antitoxin system RelE/ParE family toxin -
VTAP4600_RS26010 621184..621360 + 177 WP_172443188.1 hypothetical protein -
VTAP4600_RS19945 621487..621903 + 417 WP_102524530.1 GFA family protein -
VTAP4600_RS19950 622264..622584 + 321 WP_102524531.1 hypothetical protein -
VTAP4600_RS19955 622631..623002 + 372 WP_102524532.1 DUF805 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(86-150)

Antitoxin

Vibrio phage ICP1, Orf50

(7-85)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18616.27 Da        Isoelectric Point: 8.8085

>T293851 WP_102524526.1 NZ_LT960612:c619273-618776 [Vibrio tapetis subsp. tapetis]
MMNTVLLEKAKHDRNRFNCGIEALNNYLKIMASQQAKKDNTRTFVLEDDNDNSHIIGFYTLTMTPIDLKALPDKLQKKHQ
SSTSGGLIARLAVDDRYKGKGFGEWLLIDALRKLLAASDSVAFPVVIVDAKDGAKHFYERYGFQTFQDSENKLFITISDV
RANLG

Download         Length: 498 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9736.21 Da        Isoelectric Point: 9.8130

>AT293851 WP_102524527.1 NZ_LT960612:c619542-619270 [Vibrio tapetis subsp. tapetis]
MANTLPRITARVDVDTQNLLTKAAAIAGMSSINSFVLSAAIEKAKQVIEREQALKLSQADAMLLMDALDRPSTINSKLKA
ASDRYDSKTQ

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References