Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 22135..22783 Replicon chromosome
Accession NZ_LT960612
Organism Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag VTAP4600_RS17270 Protein ID WP_102525281.1
Coordinates 22135..22536 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag VTAP4600_RS17275 Protein ID WP_102524061.1
Coordinates 22550..22783 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VTAP4600_RS17235 17322..18527 - 1206 WP_102524054.1 DUF1611 domain-containing protein -
VTAP4600_RS17245 18911..20038 - 1128 WP_102524056.1 HD domain-containing protein -
VTAP4600_RS17250 20161..20427 - 267 WP_102524057.1 hypothetical protein -
VTAP4600_RS17255 20438..20656 - 219 WP_102524058.1 hypothetical protein -
VTAP4600_RS17260 20686..21150 - 465 WP_102524059.1 hypothetical protein -
VTAP4600_RS17270 22135..22536 - 402 WP_102525281.1 type II toxin-antitoxin system VapC family toxin Toxin
VTAP4600_RS17275 22550..22783 - 234 WP_102524061.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
VTAP4600_RS17280 23250..23925 + 676 Protein_22 SDR family oxidoreductase -
VTAP4600_RS17285 23986..25173 + 1188 WP_102524062.1 MFS transporter -
VTAP4600_RS17290 25220..26101 + 882 WP_102524063.1 DoxX family protein -
VTAP4600_RS17295 26192..26758 + 567 Protein_25 glutaredoxin 2 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 10386..39273 28887


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14788.33 Da        Isoelectric Point: 7.8042

>T293850 WP_102525281.1 NZ_LT960612:c22536-22135 [Vibrio tapetis subsp. tapetis]
MLDTCICSFIMREQPIAVLKMLQDVVGKQHRIVISAITYQEMQYGLLGKKASPKHAVLVAEFLKRVDEILPWDKVAVDAT
TEVKRSLMAKGTPIGNNDTAIAGHAIATGCVLVTNNTREFQRVEGLKLEDWVH

Download         Length: 402 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9043.07 Da        Isoelectric Point: 4.4453

>AT293850 WP_102524061.1 NZ_LT960612:c22783-22550 [Vibrio tapetis subsp. tapetis]
MRTVSIFKNGKNQAVRLPKDFEFDGVNELEIHKEGDVITLRPARPDWLSFGEQEKPDEDFMANREDVIKDEGRFNFE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References