293848

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 3652958..3654306 Replicon chromosome
Accession NZ_LT960611
Organism Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600

Toxin (Protein)


Gene name sanaT Uniprot ID B2LS98
Locus tag VTAP4600_RS16445 Protein ID WP_012397035.1
Coordinates 3653365..3654306 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID B2LS97
Locus tag VTAP4600_RS16440 Protein ID WP_012397034.1
Coordinates 3652958..3653362 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VTAP4600_RS16415 3648399..3649931 + 1533 WP_102521770.1 IS21 family transposase -
VTAP4600_RS16420 3649941..3650681 + 741 WP_012397030.1 IS21-like element helper ATPase IstB -
VTAP4600_RS16425 3650826..3651293 + 468 WP_012397031.1 hypothetical protein -
VTAP4600_RS16430 3651425..3651913 + 489 WP_131825470.1 hypothetical protein -
VTAP4600_RS16435 3652177..3652770 + 594 WP_012397033.1 tyrosine-type recombinase/integrase -
VTAP4600_RS16440 3652958..3653362 + 405 WP_012397034.1 hypothetical protein Antitoxin
VTAP4600_RS16445 3653365..3654306 + 942 WP_012397035.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
VTAP4600_RS16450 3654314..3656908 + 2595 WP_012397036.1 type I restriction-modification system subunit M -
VTAP4600_RS16455 3656901..3658160 + 1260 WP_012397037.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-300)

Antitoxin

Protein of unknown function DUF6088

(7-129)


Sequences

Toxin        


Download         Length: 314 a.a.        Molecular weight: 36177.99 Da        Isoelectric Point: 5.5269

>T293848 WP_012397035.1 NZ_LT960611:3653365-3654306 [Vibrio tapetis subsp. tapetis]
MKKLKQQFLEVSDALALGNPAIIEKDYWVVALLAELEKLTFETHQLVFAGGTALAKSNVKILRMSEDVDIKLIPSKEFDA
LSRGKKKTARKMLIEQIEQVIARSQQFTVESRLVRDEYRYVEYELKYPQQFNQAPCLRPIIKLELMETIPLLEVEDRGIQ
SLVAELYKQPQEVSAFACVSVYATLVEKVLSMLRRTMLVKRDTERKDDVTLVRHIYDVHCIDTAQTLDIESLTSLFLTVL
KEDIDRFGNQHAEFVAAPIKELRLGLQELEDNPIFRQRFQDFVTPMVFNTEPHDFDTCFASFKRIAESLIKTI

Download         Length: 942 bp

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15197.34 Da        Isoelectric Point: 10.5757

>AT293848 WP_012397034.1 NZ_LT960611:3652958-3653362 [Vibrio tapetis subsp. tapetis]
MTAADRIYQNIKRSRRYVFERKDFDGFASYDQVGRALRQLVKQGELMKLGYGLYTKARVNSLTGRPMPTNPGGSDALIRE
ILKMKGVDFEMDSLSLQSFSGESTQVPSSVHYSWNPKQFNRKLVVGNRVLNSPS

Download         Length: 405 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N8ZHR3

Antitoxin

Source ID Structure
AlphaFold DB A0A2N8ZHQ5

References