Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 3615677..3616698 | Replicon | chromosome |
| Accession | NZ_LT960611 | ||
| Organism | Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | VTAP4600_RS16280 | Protein ID | WP_102523734.1 |
| Coordinates | 3615677..3616246 (-) | Length | 190 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | VTAP4600_RS16285 | Protein ID | WP_102523735.1 |
| Coordinates | 3616246..3616698 (-) | Length | 151 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VTAP4600_RS16270 | 3612384..3614975 | - | 2592 | Protein_3131 | AAA family ATPase | - |
| VTAP4600_RS16280 | 3615677..3616246 | - | 570 | WP_102523734.1 | PIN domain-containing protein | Toxin |
| VTAP4600_RS16285 | 3616246..3616698 | - | 453 | WP_102523735.1 | helix-turn-helix domain-containing protein | Antitoxin |
| VTAP4600_RS16290 | 3617089..3617385 | - | 297 | WP_102523736.1 | hypothetical protein | - |
| VTAP4600_RS16295 | 3617653..3618117 | - | 465 | WP_102523737.1 | hypothetical protein | - |
| VTAP4600_RS16300 | 3618133..3618603 | - | 471 | WP_102523738.1 | hypothetical protein | - |
| VTAP4600_RS16305 | 3619148..3619855 | + | 708 | WP_102523739.1 | IS6 family transposase | - |
| VTAP4600_RS16310 | 3619987..3620598 | - | 612 | WP_102523740.1 | RraA family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 3619148..3619855 | 707 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 190 a.a. Molecular weight: 21476.83 Da Isoelectric Point: 5.9970
>T293846 WP_102523734.1 NZ_LT960611:c3616246-3615677 [Vibrio tapetis subsp. tapetis]
MASYTVILDACVMYPAPLRSYLMFLANTGLFRARWTEQIHDEWTRNLLKNRPELNAEQLHRTRQLMNANVPDCLIEGFEP
LIDGLTLPDVNDRHVVAAAIKGQAESIITFNLKDFPSSELEPLGLSAIHPDEFLCDMFELDSSACVKAAQQQRASLKRPP
MSQDEFLACLQKQRLPSFVSHLKSFKLML
MASYTVILDACVMYPAPLRSYLMFLANTGLFRARWTEQIHDEWTRNLLKNRPELNAEQLHRTRQLMNANVPDCLIEGFEP
LIDGLTLPDVNDRHVVAAAIKGQAESIITFNLKDFPSSELEPLGLSAIHPDEFLCDMFELDSSACVKAAQQQRASLKRPP
MSQDEFLACLQKQRLPSFVSHLKSFKLML
Download Length: 570 bp
Antitoxin
Download Length: 151 a.a. Molecular weight: 16344.65 Da Isoelectric Point: 4.4466
>AT293846 WP_102523735.1 NZ_LT960611:c3616698-3616246 [Vibrio tapetis subsp. tapetis]
MNTATKLPSAEEMALAKLGSQELSAVIEINGEAQRINVVDKSGKTHEVTIPASALNMMIEVLTQLGQGNSVSITPIHAEL
TTQEGADMLNMSRPTFIKLLDSGDIPFSRTGNRRKVAYADLMEYKNCLEENRLAALAELSALDQEMDMGY
MNTATKLPSAEEMALAKLGSQELSAVIEINGEAQRINVVDKSGKTHEVTIPASALNMMIEVLTQLGQGNSVSITPIHAEL
TTQEGADMLNMSRPTFIKLLDSGDIPFSRTGNRRKVAYADLMEYKNCLEENRLAALAELSALDQEMDMGY
Download Length: 453 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|