293845

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2564293..2565842 Replicon chromosome
Accession NZ_LT960611
Organism Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag VTAP4600_RS11435 Protein ID WP_102522911.1
Coordinates 2564541..2565842 (+) Length 434 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID A0A2N8ZEV9
Locus tag VTAP4600_RS11430 Protein ID WP_017034177.1
Coordinates 2564293..2564541 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VTAP4600_RS11410 2561184..2561789 + 606 WP_102522907.1 DUF4433 domain-containing protein -
VTAP4600_RS11415 2561804..2562871 + 1068 WP_102522908.1 macro domain-containing protein -
VTAP4600_RS11420 2562935..2563510 - 576 WP_102522909.1 DUF4433 domain-containing protein -
VTAP4600_RS11430 2564293..2564541 + 249 WP_017034177.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
VTAP4600_RS11435 2564541..2565842 + 1302 WP_102522911.1 type II toxin-antitoxin system HipA family toxin Toxin
VTAP4600_RS11440 2565986..2566786 - 801 WP_102523972.1 RecX family transcriptional regulator -
VTAP4600_RS11445 2566950..2568479 - 1530 WP_102521342.1 transposase -
VTAP4600_RS11450 2568663..2570009 - 1347 WP_102522912.1 magnesium transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(3-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(15-64)


Sequences

Toxin        


Download         Length: 434 a.a.        Molecular weight: 48875.51 Da        Isoelectric Point: 9.1464

>T293845 WP_102522911.1 NZ_LT960611:2564541-2565842 [Vibrio tapetis subsp. tapetis]
MQKLNAYMNGELVGTLNKQKNGAHTFQYDKTWVTSDKSRPLSLSLKLQLPPITSDSVINYFDNLLPDSPKVRDRIVNRYK
ASSKQPFDLLKEVGKDSVGAIALISPEQPYKNESLNYQVLDDKKLDAVLSAYKSDIPLGMVEEEEDFRISVAGVQEKTAL
LFLDEQWCIPKGNTPTTHIIKLPIGEIQQANATLDLKDSVENEYLCIELAKALGFAVPNVHMLKTDNLKALAVERFDRRW
TKDKANLLRLPQEDMCQVFGMPSSIKYEPQGGPGISEIMKLLMGSSNALKDQYNFMKFQVFQWIIGATDGHAKNYSIYIE
KGGSYRLTPFYDILSAYPLLGGRGLNIRKIKLAMGLKATRGKKYEINKILPRHFLDTAKAVNFSQDKMQKILNELKGEFP
EAILQVKAKLPEDFPEKISDSIFENATKILSKI

Download         Length: 1302 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9396.69 Da        Isoelectric Point: 4.9816

>AT293845 WP_017034177.1 NZ_LT960611:2564293-2564541 [Vibrio tapetis subsp. tapetis]
MIYSPKQLADMMLLIRQKNGWTQSELAKRVGIKQATISNFENSPDKTTLSTFFKLIQAMELTLSIQEKAQVSSQDSQDDE
NW

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N8ZEV9

References