293841

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2309916..2310544 Replicon chromosome
Accession NZ_LT934425
Organism Candidatus Kuenenia stuttgartiensis isolate kuenenia_mbr1_ru-nijmegen

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KSMBR1_RS10615 Protein ID WP_099325311.1
Coordinates 2310143..2310544 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KSMBR1_RS10610 Protein ID WP_099325310.1
Coordinates 2309916..2310143 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSMBR1_RS10600 2307043..2308545 + 1503 WP_099325308.1 DUF2779 domain-containing protein -
KSMBR1_RS10605 2308851..2309324 + 474 WP_099325309.1 HEAT repeat domain-containing protein -
KSMBR1_RS10610 2309916..2310143 + 228 WP_099325310.1 antitoxin Antitoxin
KSMBR1_RS10615 2310143..2310544 + 402 WP_099325311.1 type II toxin-antitoxin system VapC family toxin Toxin
KSMBR1_RS10620 2310956..2311540 - 585 WP_099325312.1 MBL fold metallo-hydrolase -
KSMBR1_RS10625 2311598..2312242 - 645 WP_099325313.1 pentapeptide repeat-containing protein -
KSMBR1_RS10630 2312282..2313079 - 798 WP_099325314.1 HD domain-containing protein -
KSMBR1_RS10635 2313198..2315081 - 1884 WP_099324133.1 IS1634 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14909.40 Da        Isoelectric Point: 7.8719

>T293841 WP_099325311.1 NZ_LT934425:2310143-2310544 [Candidatus Kuenenia stuttgartiensis]
MKCMLDTNICIYLIKRKNPKILAYLKKHDIGEVGISSITLAELQYGVANSNYIQRNREALHEFILPLEIADFDEKVAEVY
GNVRANLEKAGTPIGSMDMLIGAHAMSLGVTLVSNNTREFNRIKGLKVVDWTI

Download         Length: 402 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8655.89 Da        Isoelectric Point: 8.7074

>AT293841 WP_099325310.1 NZ_LT934425:2309916-2310143 [Candidatus Kuenenia stuttgartiensis]
VKTAKIFQNGQSQAVRLPKEFRFEGDHVFIKKSGNIVMLIPAKESWNSLVDSLDKFTDDFMGERKQLDTQTREPL

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References