Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3613347..3613878 Replicon chromosome
Accession NZ_LT907988
Organism Orrella dioscoreae isolate Orrdi1

Toxin (Protein)


Gene name relE Uniprot ID A0A1C3K498
Locus tag ODI_RS16720 Protein ID WP_067755620.1
Coordinates 3613347..3613622 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ODI_RS16725 Protein ID WP_067755617.1
Coordinates 3613660..3613878 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ODI_RS16705 3608722..3611010 - 2289 WP_098020929.1 NADP-dependent malic enzyme -
ODI_RS16710 3611023..3611940 - 918 WP_067755625.1 hypothetical protein -
ODI_RS16715 3612071..3613231 + 1161 WP_067755623.1 pyridoxal phosphate-dependent aminotransferase -
ODI_RS16720 3613347..3613622 - 276 WP_067755620.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ODI_RS16725 3613660..3613878 - 219 WP_067755617.1 hypothetical protein Antitoxin
ODI_RS16730 3613981..3614793 - 813 WP_067755614.1 lytic transglycosylase domain-containing protein -
ODI_RS16735 3614889..3616433 + 1545 WP_067755611.1 UbiD family decarboxylase -
ODI_RS16740 3616455..3617470 - 1016 Protein_3299 hemin-degrading factor -
ODI_RS16745 3617534..3617926 - 393 WP_067755608.1 hypothetical protein -
ODI_RS16750 3617972..3618406 - 435 WP_067755605.1 phage holin family protein -
ODI_RS16755 3618463..3618774 - 312 WP_067755602.1 DUF883 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10499.89 Da        Isoelectric Point: 4.6438

>T293817 WP_067755620.1 NZ_LT907988:c3613622-3613347 [Orrella dioscoreae]
MLLIFWNAAAVDDLDDIIDYIAEYDVHAAIDMHERIESAVHPASEHPYLYRPGRVPGTREIVAHPNYVVVYEVRADRIEV
MAVLHARQEYP

Download         Length: 276 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8145.16 Da        Isoelectric Point: 6.4673

>AT293817 WP_067755617.1 NZ_LT907988:c3613878-3613660 [Orrella dioscoreae]
MSVALSPIVSEFETEEQAASHDLWFRAKVQASRDDPRPSIPHDEAMARIREKLAAKLADQEAAPAMRRSRDR

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C3K498

Antitoxin

Source ID Structure

References