Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3476711..3477405 Replicon chromosome
Accession NZ_LT907988
Organism Orrella dioscoreae isolate Orrdi1

Toxin (Protein)


Gene name VapC1 Uniprot ID -
Locus tag ODI_RS16190 Protein ID WP_067752093.1
Coordinates 3476998..3477405 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID A0A1C3K0R5
Locus tag ODI_RS16185 Protein ID WP_067752091.1
Coordinates 3476711..3476998 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ODI_RS16175 3472131..3475379 - 3249 WP_067752085.1 carbamoyl-phosphate synthase large subunit -
ODI_RS16180 3475389..3476543 - 1155 WP_067752088.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
ODI_RS16185 3476711..3476998 + 288 WP_067752091.1 hypothetical protein Antitoxin
ODI_RS16190 3476998..3477405 + 408 WP_067752093.1 type II toxin-antitoxin system VapC family toxin Toxin
ODI_RS16195 3477504..3478463 + 960 WP_067752096.1 transaldolase -
ODI_RS16200 3478783..3480480 + 1698 WP_067752099.1 L-lactate permease -
ODI_RS16205 3480540..3481769 - 1230 WP_067752102.1 YeeE/YedE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15257.73 Da        Isoelectric Point: 9.1310

>T293816 WP_067752093.1 NZ_LT907988:3476998-3477405 [Orrella dioscoreae]
MRYLLDTNILIYLIKHRPPSVAERIAQLALDDALHMSFVSWAELLKGAERSTRADTVRKQLHKLAQHIPVLYETSHDMCL
HHARLGAMFKSQGKPIGANDLWIAAHALAEGCVLVTNNTREFSRVPGLPLQNWVQ

Download         Length: 408 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10426.63 Da        Isoelectric Point: 4.5859

>AT293816 WP_067752091.1 NZ_LT907988:3476711-3476998 [Orrella dioscoreae]
MPTTLTSRIFNNGNSQAVRIPLAFRLDAQRVSITRKENGDLLLHPLPDAPADRAAAIQAALQGFGELDDATQRAFIAELE
GNRAQPEPDQEREAF

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3K0R5

References