Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 913507..914105 Replicon chromosome
Accession NZ_LT907988
Organism Orrella dioscoreae isolate Orrdi1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ODI_RS04120 Protein ID WP_067752359.1
Coordinates 913806..914105 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag ODI_RS04115 Protein ID WP_067752229.1
Coordinates 913507..913803 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ODI_RS04095 908511..909851 + 1341 WP_067752239.1 DUF3100 domain-containing protein -
ODI_RS04100 909863..910756 + 894 WP_067752237.1 NAD(P)-dependent oxidoreductase -
ODI_RS04105 910753..912270 + 1518 WP_067752234.1 aldehyde dehydrogenase family protein -
ODI_RS04110 912307..913479 + 1173 WP_067752232.1 amidohydrolase -
ODI_RS04115 913507..913803 - 297 WP_067752229.1 putative addiction module antidote protein Antitoxin
ODI_RS04120 913806..914105 - 300 WP_067752359.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ODI_RS04125 914293..915681 - 1389 WP_067752226.1 L-serine ammonia-lyase -
ODI_RS04130 915797..916729 + 933 WP_067752223.1 LysR family transcriptional regulator -
ODI_RS04135 916755..918359 - 1605 WP_082985254.1 NAD(P)H-hydrate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(40-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11293.04 Da        Isoelectric Point: 11.2365

>T293814 WP_067752359.1 NZ_LT907988:c914105-913806 [Orrella dioscoreae]
MIRVYTTPTFDRWFAQIDDTLTAKRIQVRIRRLQLGNHGDWAPIGEGVAELRIHHGPGYRVVFMPRTTDIIVLLAGGDKS
TQPRDIRAALSLARQLRET

Download         Length: 300 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10692.20 Da        Isoelectric Point: 6.9792

>AT293814 WP_067752229.1 NZ_LT907988:c913803-913507 [Orrella dioscoreae]
MTRPTLREWDSADHLGTEKDRVLYLQACMEEAGDDATFIAKALGDIARAKGMTQLARDTGLGRESLYKALSGEGNPSFAT
ILKVTRALGIRLQPQLQA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References