Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 568813..569342 Replicon chromosome
Accession NZ_LT907988
Organism Orrella dioscoreae isolate Orrdi1

Toxin (Protein)


Gene name yoeB Uniprot ID A0A1C3K563
Locus tag ODI_RS02690 Protein ID WP_067756494.1
Coordinates 568813..569079 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1C3K4Y6
Locus tag ODI_RS02695 Protein ID WP_067756497.1
Coordinates 569076..569342 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ODI_RS02680 564347..564556 + 210 WP_067756488.1 hypothetical protein -
ODI_RS02685 564703..568644 + 3942 WP_067756491.1 FAD/FMN-binding oxidoreductase -
ODI_RS02690 568813..569079 - 267 WP_067756494.1 Txe/YoeB family addiction module toxin Toxin
ODI_RS02695 569076..569342 - 267 WP_067756497.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ODI_RS02700 569476..570768 - 1293 WP_067756500.1 TRAP transporter large permease subunit -
ODI_RS02705 570781..571299 - 519 WP_067756503.1 TRAP transporter small permease subunit -
ODI_RS02710 571410..572378 - 969 WP_067756504.1 TRAP transporter substrate-binding protein -
ODI_RS02715 572479..573252 - 774 WP_067756507.1 LamB/YcsF family protein -
ODI_RS02720 573249..574259 - 1011 WP_067756510.1 biotin-dependent carboxyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10597.07 Da        Isoelectric Point: 6.8520

>T293813 WP_067756494.1 NZ_LT907988:c569079-568813 [Orrella dioscoreae]
MTPPPKGVCFDKHGWEDYLSWQDDPKKRKRINQLIDHTLRTPFEGIGKPEPLKGDLQGFWSRRIDEEHRLVYCVEDEQLI
VIQCRYHY

Download         Length: 267 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9743.03 Da        Isoelectric Point: 7.3166

>AT293813 WP_067756497.1 NZ_LT907988:c569342-569076 [Orrella dioscoreae]
MKIVNYTDARNGLKAVLDQVSDDADVTVITRRDGPDAVVMSKAHYDGIMETLHLLRSPANAARLRVSVANVRDKAYQARN
LIHPDEQA

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C3K563

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3K4Y6

References