Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 301450..302098 Replicon chromosome
Accession NZ_LT906480
Organism Stenotrophomonas maltophilia strain NCTC10257

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CKW06_RS01455 Protein ID WP_005407702.1
Coordinates 301450..301755 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag CKW06_RS01460 Protein ID WP_005407703.1
Coordinates 301796..302098 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKW06_RS01425 297404..298195 - 792 WP_169922258.1 zinc-dependent peptidase -
CKW06_RS01430 298162..298440 - 279 WP_005411956.1 hypothetical protein -
CKW06_RS01435 298585..299550 + 966 WP_024956165.1 bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor -
CKW06_RS01440 299547..300278 + 732 WP_005407698.1 type III pantothenate kinase -
CKW06_RS01445 300288..301142 + 855 WP_005411958.1 SPOR domain-containing protein -
CKW06_RS01455 301450..301755 + 306 WP_005407702.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CKW06_RS01460 301796..302098 + 303 WP_005407703.1 putative addiction module antidote protein Antitoxin
CKW06_RS01465 302356..302655 - 300 WP_143568664.1 hypothetical protein -
CKW06_RS01470 302736..303143 - 408 WP_024956163.1 hypothetical protein -
CKW06_RS01475 303738..304508 + 771 WP_005411960.1 DUF3011 domain-containing protein -
CKW06_RS01480 304533..304880 - 348 WP_024956162.1 hypothetical protein -
CKW06_RS01485 305011..305931 + 921 WP_005407709.1 arginase -
CKW06_RS01490 306092..306229 + 138 WP_005407710.1 entericidin A/B family lipoprotein -
CKW06_RS01495 306437..306658 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 260123..304880 44757


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11444.15 Da        Isoelectric Point: 10.9897

>T293783 WP_005407702.1 NZ_LT906480:301450-301755 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGHPGDHRYLADGVSELRIDAGPGYRVYYTQRGRQLVILLVGGDKGS
QQRDIEKAKEIARALRASNWL

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10703.27 Da        Isoelectric Point: 7.2780

>AT293783 WP_005407703.1 NZ_LT906480:301796-302098 [Stenotrophomonas maltophilia]
MAIKKKVELEAFDVAEHLHTPKEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FSTILKVTRALGVRLHASAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References