Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 65319..65854 Replicon chromosome
Accession NZ_LT906479
Organism Serratia ficaria strain NCTC12148

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CKW09_RS00290 Protein ID WP_073970302.1
Coordinates 65579..65854 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A240A6T5
Locus tag CKW09_RS00285 Protein ID WP_061797877.1
Coordinates 65319..65579 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKW09_RS00265 60649..61287 + 639 WP_061797966.1 DcrB-related protein -
CKW09_RS00270 61334..61939 + 606 WP_095094909.1 glutathione S-transferase -
CKW09_RS00275 62008..63399 + 1392 WP_095094912.1 L-seryl-tRNA(Sec) selenium transferase -
CKW09_RS00280 63396..65237 + 1842 WP_095094915.1 selenocysteine-specific translation elongation factor -
CKW09_RS00285 65319..65579 + 261 WP_061797877.1 ribbon-helix-helix domain-containing protein Antitoxin
CKW09_RS00290 65579..65854 + 276 WP_073970302.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CKW09_RS00295 65916..67163 - 1248 WP_095094918.1 MFS transporter -
CKW09_RS00300 67404..68396 + 993 WP_095094923.1 acyltransferase -
CKW09_RS00305 68391..69311 - 921 WP_061797880.1 helix-turn-helix domain-containing protein -
CKW09_RS00310 69314..69865 - 552 WP_095094926.1 isochorismatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10619.32 Da        Isoelectric Point: 10.0333

>T293768 WP_073970302.1 NZ_LT906479:65579-65854 [Serratia ficaria]
MDLKWTSKALSDLARLFELLASVNHAAAANTVQALVAAPKVLRDNPRIGEKLDEFMPHEVRRILVGRYEMRYQLQSSTIY
ILRIWHTREER

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9727.14 Da        Isoelectric Point: 5.1255

>AT293768 WP_061797877.1 NZ_LT906479:65319-65579 [Serratia ficaria]
MNTKVITAHVPLPLVEKVDEMAAKLERSRGWIVKQALTAWLDQEEERRRLTLAALTDVEQQNVIDHESVEAWAASLSSDK
PLPVPR

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A240A6T5

References