Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3325129..3325666 Replicon chromosome
Accession NZ_LT906476
Organism Legionella pneumophila strain NCTC11286

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CKV96_RS15105 Protein ID WP_027266055.1
Coordinates 3325129..3325425 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CKV96_RS15110 Protein ID WP_027266056.1
Coordinates 3325415..3325666 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKV96_RS15080 3321221..3322117 - 897 WP_027266053.1 hypothetical protein -
CKV96_RS15085 3322385..3322576 + 192 WP_014327021.1 hypothetical protein -
CKV96_RS15090 3323047..3323586 - 540 WP_062730332.1 sel1 repeat family protein -
CKV96_RS15095 3323546..3324199 - 654 WP_027266054.1 hypothetical protein -
CKV96_RS15100 3324558..3325040 - 483 WP_014842908.1 hypothetical protein -
CKV96_RS15105 3325129..3325425 - 297 WP_027266055.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CKV96_RS15110 3325415..3325666 - 252 WP_027266056.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CKV96_RS15115 3325830..3327035 + 1206 WP_061638482.1 ISNCY family transposase -
CKV96_RS15120 3327208..3327947 - 740 Protein_2890 site-specific integrase -
CKV96_RS15125 3327986..3329125 - 1140 WP_134984249.1 DUF3800 domain-containing protein -
CKV96_RS15835 3329243..3329608 - 366 WP_197697735.1 recombinase family protein -
CKV96_RS15840 3329590..3329787 - 198 WP_197697736.1 recombinase family protein -
CKV96_RS15805 3329875..3330015 + 141 WP_154219844.1 hypothetical protein -
CKV96_RS15135 3330040..3330543 - 504 WP_027265579.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-60)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11512.36 Da        Isoelectric Point: 10.3916

>T293766 WP_027266055.1 NZ_LT906476:c3325425-3325129 [Legionella pneumophila]
MIYELHFHPLALKEWKKLGKNLQEEFKKVLKRRLENPHVASASLRGSLKNCYKIKLRQSGYRLVYQVNDNKLIVTVIAVG
KRNKNVVYDDADNRQEDS

Download         Length: 297 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9271.70 Da        Isoelectric Point: 5.0359

>AT293766 WP_027266056.1 NZ_LT906476:c3325666-3325415 [Legionella pneumophila]
MQTLFATQVASISELKKNPTKLINDAHGKPVAILNHNTAAAYLIPVETFEKLMDLIDENELHKIVEERLSAPFTSIKVNI
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References