Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 2909244..2909769 Replicon chromosome
Accession NZ_LT906473
Organism Corynebacterium cystitidis strain NCTC11863

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CKV99_RS13705 Protein ID WP_092258248.1
Coordinates 2909244..2909498 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CKV99_RS13710 Protein ID WP_092258246.1
Coordinates 2909509..2909769 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKV99_RS13675 2904514..2904813 + 300 WP_197697197.1 HigA family addiction module antidote protein -
CKV99_RS13680 2904870..2905604 - 735 WP_092258260.1 ABC transporter permease -
CKV99_RS13685 2905604..2906353 - 750 WP_092258257.1 ABC transporter permease -
CKV99_RS13690 2906350..2907261 - 912 WP_092258254.1 ABC transporter ATP-binding protein -
CKV99_RS13695 2907322..2907993 - 672 WP_169872657.1 response regulator transcription factor -
CKV99_RS13700 2907990..2909090 - 1101 WP_143063430.1 two-component sensor histidine kinase -
CKV99_RS13705 2909244..2909498 - 255 WP_092258248.1 Txe/YoeB family addiction module toxin Toxin
CKV99_RS13710 2909509..2909769 - 261 WP_092258246.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CKV99_RS13715 2910054..2911136 + 1083 Protein_2668 hypothetical protein -
CKV99_RS13720 2911143..2911850 - 708 WP_092258241.1 hypothetical protein -
CKV99_RS13725 2911971..2912402 - 432 WP_092258238.1 hypothetical protein -
CKV99_RS13730 2912459..2912896 - 438 WP_092258235.1 hypothetical protein -
CKV99_RS13735 2913183..2914436 + 1254 WP_092258231.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10333.73 Da        Isoelectric Point: 9.8012

>T293742 WP_092258248.1 NZ_LT906473:c2909498-2909244 [Corynebacterium cystitidis]
MNISWSTHAWEDYVWWQQHDRKMLKRINQLIRDIIRNGTRGIGKPEPLKHDFSGYWSRRINEEHRLIYSIQDSTIFIAGC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9630.77 Da        Isoelectric Point: 4.1957

>AT293742 WP_092258246.1 NZ_LT906473:c2909769-2909509 [Corynebacterium cystitidis]
MKTISFTESRNNYAAVMDSVIDDREPVVITRTGRDPVVMIALDDYNSLQETAYLMRSPENSKRLRESIAELEAGGGVVHE
LLDEEA

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References