Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2165611..2166056 Replicon chromosome
Accession NZ_LT906473
Organism Corynebacterium cystitidis strain NCTC11863

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CKV99_RS10300 Protein ID WP_092256659.1
Coordinates 2165895..2166056 (-) Length 54 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CKV99_RS10295 Protein ID WP_092256657.1
Coordinates 2165611..2165904 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKV99_RS10260 2160801..2161001 + 201 WP_092256648.1 hypothetical protein -
CKV99_RS10265 2161339..2162100 - 762 WP_157728429.1 hypothetical protein -
CKV99_RS10270 2162263..2163117 - 855 WP_092256654.1 hypothetical protein -
CKV99_RS14575 2163209..2163553 - 345 WP_197697184.1 YdcF family protein -
CKV99_RS10290 2164210..2164971 - 762 WP_092256812.1 hypothetical protein -
CKV99_RS10295 2165611..2165904 - 294 WP_092256657.1 putative addiction module antidote protein Antitoxin
CKV99_RS10300 2165895..2166056 - 162 WP_092256659.1 hypothetical protein Toxin
CKV99_RS10305 2166423..2167166 - 744 WP_092256662.1 thioesterase II family protein -
CKV99_RS10310 2167163..2171029 - 3867 WP_092256665.1 non-ribosomal peptide synthetase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-45)

Antitoxin

Uncharacterized protein HI1420

(4-91)


Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 6064.10 Da        Isoelectric Point: 10.3496

>T293740 WP_092256659.1 NZ_LT906473:c2166056-2165895 [Corynebacterium cystitidis]
MRIHVGPGYRIYYMARGNQIMLLVIGGDKSTQQRDIAKAKRLATEIIKEGSWE

Download         Length: 162 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10251.61 Da        Isoelectric Point: 4.5702

>AT293740 WP_092256657.1 NZ_LT906473:c2165904-2165611 [Corynebacterium cystitidis]
MGVKISTWDASEYLETKEDIAAYLNAALEDGDPALWQAALGDVAKARGMTAIAREAGVGRESLYKSLSENGNPSWQTVTK
VLAALGLKVEVKANALA

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References