Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 1569188..1569765 Replicon chromosome
Accession NZ_LT906469
Organism Mycolicibacter terrae strain NCTC10856

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag CKW33_RS07310 Protein ID WP_085259683.1
Coordinates 1569188..1569571 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag CKW33_RS07315 Protein ID WP_085259684.1
Coordinates 1569568..1569765 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKW33_RS07285 1564832..1565875 + 1044 WP_085259679.1 heat-inducible transcriptional repressor HrcA -
CKW33_RS07290 1565909..1567060 + 1152 WP_085259680.1 molecular chaperone DnaJ -
CKW33_RS07295 1567064..1567807 + 744 WP_085259681.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -
CKW33_RS07300 1567813..1568514 + 702 WP_085259682.1 AraC family transcriptional regulator -
CKW33_RS07305 1568493..1569140 - 648 WP_085259701.1 methyltransferase domain-containing protein -
CKW33_RS07310 1569188..1569571 - 384 WP_085259683.1 Fic family protein Toxin
CKW33_RS07315 1569568..1569765 - 198 WP_085259684.1 antitoxin Phd Antitoxin
CKW33_RS07320 1569899..1570951 + 1053 WP_085259685.1 PhoH family protein -
CKW33_RS07325 1570948..1571484 + 537 WP_085259686.1 rRNA maturation RNase YbeY -
CKW33_RS07330 1571481..1572779 + 1299 WP_085259687.1 hemolysin family protein -
CKW33_RS07335 1572879..1573775 + 897 WP_085259688.1 GTPase Era -
CKW33_RS07340 1573825..1574499 + 675 WP_165758668.1 DUF5642 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(28-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13589.27 Da        Isoelectric Point: 3.8561

>T293734 WP_085259683.1 NZ_LT906469:c1569571-1569188 [Mycolicibacter terrae]
MTEFLDRDDLLVAGAFAVSHACEVGDYGLLDAAVARPQATVFGVDAYPDLYAKAAALLQSLARNHALVDGNMRTAWASAW
TFLYLNACELSPDFDVDAAEVFMNDVAQRGELPVEDIAATLASFAVT

Download         Length: 384 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7022.95 Da        Isoelectric Point: 11.5969

>AT293734 WP_085259684.1 NZ_LT906469:c1569765-1569568 [Mycolicibacter terrae]
VPSLNITFTEEELAAVRAAAGEQNLSLRVFAHRAVVTAASDHRRRVAEAAALVAQRSAELNRRLA

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References