Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 1599176..1599698 Replicon chromosome
Accession NZ_LT906464
Organism Staphylococcus muscae strain NCTC13833

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag CKV93_RS07875 Protein ID WP_095117495.1
Coordinates 1599176..1599397 (-) Length 74 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag CKV93_RS07880 Protein ID WP_095117496.1
Coordinates 1599411..1599698 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKV93_RS07855 1595185..1596390 + 1206 WP_095117493.1 rod shape-determining protein RodA -
CKV93_RS07860 1596461..1596622 - 162 WP_157728697.1 hypothetical protein -
CKV93_RS07865 1596687..1598870 - 2184 WP_095118146.1 heavy metal translocating P-type ATPase -
CKV93_RS07870 1598970..1599173 - 204 WP_095117494.1 cation transporter -
CKV93_RS07875 1599176..1599397 - 222 WP_095117495.1 heavy-metal-associated domain-containing protein Toxin
CKV93_RS07880 1599411..1599698 - 288 WP_095117496.1 copper-sensing transcriptional repressor CsoR Antitoxin
CKV93_RS07885 1599842..1601332 + 1491 WP_095117497.1 cardiolipin synthase -
CKV93_RS07890 1601353..1601991 + 639 WP_095117498.1 HD domain-containing protein -
CKV93_RS07895 1602060..1602929 - 870 WP_095117499.1 membrane protein insertase YidC -
CKV93_RS07900 1603018..1603656 - 639 WP_095118147.1 thiamine phosphate synthase -
CKV93_RS07905 1603646..1604452 - 807 WP_095117500.1 hydroxyethylthiazole kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Heavy metal-associated domain, HMA

(5-63)

Antitoxin

Metal-sensitive transcriptional repressor

(12-90)


Sequences

Toxin        


Download         Length: 74 a.a.        Molecular weight: 8234.21 Da        Isoelectric Point: 4.5284

>T293732 WP_095117495.1 NZ_LT906464:c1599397-1599176 [Staphylococcus muscae]
VHSKVWLSGLSSEEQKKQLESRLSNMIGVEAVEVNTESQMVTLTYETPANLNTLEKEIYDAGYPVINSYKGER

Download         Length: 222 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10900.45 Da        Isoelectric Point: 6.7505

>AT293732 WP_095117496.1 NZ_LT906464:c1599698-1599411 [Staphylococcus muscae]
MTEHANHSDVTKRNLQSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNGVASKLLEHHMKGCIMHKVEGGNEHE
AMDELLVTFQKLMKD

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References