Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1437142..1437918 Replicon chromosome
Accession NZ_LT906464
Organism Staphylococcus muscae strain NCTC13833

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag CKV93_RS10570 Protein ID WP_169712259.1
Coordinates 1437142..1437300 (-) Length 53 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag CKV93_RS06965 Protein ID WP_095117350.1
Coordinates 1437319..1437918 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKV93_RS06950 1433419..1434945 - 1527 WP_095117347.1 exopolyphosphatase -
CKV93_RS06955 1434967..1436352 - 1386 WP_095117348.1 class II fumarate hydratase -
CKV93_RS06960 1436532..1436936 - 405 WP_095117349.1 hypothetical protein -
CKV93_RS10570 1437142..1437300 - 159 WP_169712259.1 hypothetical protein Toxin
CKV93_RS06965 1437319..1437918 - 600 WP_095117350.1 glucosamine-6-phosphate isomerase Antitoxin
CKV93_RS06970 1437942..1439117 - 1176 WP_095117351.1 N-acetylglucosamine-6-phosphate deacetylase -
CKV93_RS06975 1439138..1439608 - 471 WP_095117352.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
CKV93_RS06980 1439608..1440738 - 1131 WP_095117353.1 tRNA epoxyqueuosine(34) reductase QueG -
CKV93_RS06985 1440897..1441619 - 723 WP_095117354.1 amino acid ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(131-195)


Sequences

Toxin        


Download         Length: 53 a.a.        Molecular weight: 6211.59 Da        Isoelectric Point: 3.9861

>T293730 WP_169712259.1 NZ_LT906464:c1437300-1437142 [Staphylococcus muscae]
MNKQENEHGMVDSFEEVVELGKEMEQISEENDEQKYEQPHEEAVRSDRETDK

Download         Length: 159 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22242.24 Da        Isoelectric Point: 5.6169

>AT293730 WP_095117350.1 NZ_LT906464:c1437918-1437319 [Staphylococcus muscae]
MAMNFKIFKDQETAATFVADILRKQFNNNPTTIAGIHLKNDNVPVSAALQENVEKNPVDFSQIHILDYDNQTNYYKALGV
PEKQIHEIPEDEKVEAFIKHHAKTKENKGKLTLQVVTIDTDGSIGIPMNDAVLTAREIVLVLTGAEKAEVTRKLYEENGS
TTFIPSSLKSHRMVNVVLDEAAAQGLPEDVRTYFSVRFA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References