Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 858098..858848 Replicon chromosome
Accession NZ_LT906462
Organism Mammaliicoccus stepanovicii strain NCTC13839

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag CKV64_RS12245 Protein ID WP_158245683.1
Coordinates 858711..858848 (+) Length 46 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag CKV64_RS04325 Protein ID WP_095087193.1
Coordinates 858098..858697 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKV64_RS04305 854077..854838 + 762 WP_095087186.1 acetylglutamate kinase -
CKV64_RS04310 855035..856162 + 1128 WP_095087188.1 tRNA epoxyqueuosine(34) reductase QueG -
CKV64_RS04315 856166..856639 + 474 WP_095087190.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
CKV64_RS04320 856899..858050 + 1152 WP_095087191.1 N-acetylglucosamine-6-phosphate deacetylase -
CKV64_RS04325 858098..858697 + 600 WP_095087193.1 glucosamine-6-phosphate isomerase Antitoxin
CKV64_RS12245 858711..858848 + 138 WP_158245683.1 hypothetical protein Toxin
CKV64_RS04330 859010..860398 + 1389 WP_095087195.1 class II fumarate hydratase -
CKV64_RS04335 860486..862012 + 1527 WP_095087197.1 Ppx/GppA family phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(134-195)


Sequences

Toxin        


Download         Length: 46 a.a.        Molecular weight: 5487.80 Da        Isoelectric Point: 3.7951

>T293729 WP_158245683.1 NZ_LT906462:858711-858848 [Mammaliicoccus stepanovicii]
MDKHIEDENEMVRDLDDVKELGKEMEQISEQNDEDYEEKKEEQES

Download         Length: 138 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22284.20 Da        Isoelectric Point: 4.7547

>AT293729 WP_095087193.1 NZ_LT906462:858098-858697 [Mammaliicoccus stepanovicii]
MALNFKVFETKGIATRYVADLVRKQFNGDSTSVVGINLDSENTSFFDELLDDVKKNPVDFSQIHILDYDGKADYYTELGV
PTKQVVKAEAKNDVESLIKDKVNTDKKKNKLMLDVITLTEDSDTGLDYDSEIHPAREVIVLVTGKEKAQAIKKLYEEPVS
SSVASAKLKQHRMVTVVLDNEAAQGLPEDVRSYFTIQFS

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References