293728

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 680745..681284 Replicon chromosome
Accession NZ_LT906462
Organism Mammaliicoccus stepanovicii strain NCTC13839

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag CKV64_RS03325 Protein ID WP_095086751.1
Coordinates 680913..681284 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag CKV64_RS03320 Protein ID WP_095086748.1
Coordinates 680745..680912 (+) Length 56 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKV64_RS03295 676621..677100 + 480 WP_095086734.1 PH domain-containing protein -
CKV64_RS03300 677090..678622 + 1533 WP_095086737.1 PH domain-containing protein -
CKV64_RS03305 678606..679073 + 468 WP_095086740.1 PH domain-containing protein -
CKV64_RS03310 679094..679462 + 369 WP_095086743.1 holo-ACP synthase -
CKV64_RS03315 679510..680658 + 1149 WP_095086746.1 alanine racemase -
CKV64_RS03320 680745..680912 + 168 WP_095086748.1 antitoxin MazE Antitoxin
CKV64_RS03325 680913..681284 + 372 WP_095086751.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
CKV64_RS03330 681388..682392 + 1005 WP_095086754.1 PP2C family protein-serine/threonine phosphatase -
CKV64_RS03335 682465..682791 + 327 WP_095086757.1 anti-sigma factor antagonist -
CKV64_RS03340 682793..683269 + 477 WP_095086760.1 anti-sigma B factor RsbW -
CKV64_RS03345 683244..684014 + 771 WP_095086764.1 RNA polymerase sigma factor SigB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-109)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13662.84 Da        Isoelectric Point: 9.9193

>T293728 WP_095086751.1 NZ_LT906462:680913-681284 [Mammaliicoccus stepanovicii]
MRRGDVYLADLSPVTGSEQGGTRPVVIIQNDTGNRYSPTVIVAAITGKINKAKIPTHVEIEAAKYKLDRDSVILLEQIRT
IDKKRLKEKLTYLSDAKMKEVDLAIAISLNLTLQHKFDTLGNT

Download         Length: 372 bp

Antitoxin


Download         Length: 56 a.a.        Molecular weight: 6122.56 Da        Isoelectric Point: 4.0121

>AT293728 WP_095086748.1 NZ_LT906462:680745-680912 [Mammaliicoccus stepanovicii]
MTSLTQNRTQNLEQTLKEGYRSMADLNLSLASEAYYSECEACDSNESHLTSSNGE

Download         Length: 168 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References