Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pezAT/zeta-ParD
Location 2902931..2903883 Replicon chromosome
Accession NZ_LT906450
Organism Rhodococcus rhodochrous strain NCTC10210

Toxin (Protein)


Gene name pezT Uniprot ID -
Locus tag CKW34_RS13315 Protein ID WP_059384167.1
Coordinates 2902931..2903500 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name pezA Uniprot ID -
Locus tag CKW34_RS13320 Protein ID WP_059384166.1
Coordinates 2903497..2903883 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKW34_RS13315 2902931..2903500 - 570 WP_059384167.1 zeta toxin family protein Toxin
CKW34_RS13320 2903497..2903883 - 387 WP_059384166.1 hypothetical protein Antitoxin
CKW34_RS13325 2904090..2905160 + 1071 WP_059384165.1 class I SAM-dependent methyltransferase -
CKW34_RS13330 2905228..2905593 + 366 WP_059384164.1 HNH endonuclease -
CKW34_RS13335 2905626..2906402 - 777 WP_155418964.1 CPBP family intramembrane metalloprotease -
CKW34_RS13340 2907559..2908491 - 933 WP_059384162.1 TAXI family TRAP transporter solute-binding subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(4-136)

Antitoxin

ParD-like antitoxin of type II bacterial toxin-antitoxin system

(7-79)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 20455.60 Da        Isoelectric Point: 10.0841

>T293695 WP_059384167.1 NZ_LT906450:c2903500-2902931 [Rhodococcus rhodochrous]
MRRLDLIVGPNGSGKSTFVELSLAPLLPCSVFVNADVIARQRWPDRAEEMSYEAAQLAAAARDRLLRQGRSFIAETVFSH
PSKLELIDRAHEAGFTVVLHVMLVPETMSVLRVQHRVAAGGHAVPEDKIRARYRRLWPLVAEAIGRADQASVYDTASGTP
VVVARFAGGVPVGAVRWPGWAPAALTGLG

Download         Length: 570 bp

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14033.47 Da        Isoelectric Point: 4.7075

>AT293695 WP_059384166.1 NZ_LT906450:c2903883-2903497 [Rhodococcus rhodochrous]
MTSSTDKVTRFDAELVDSAIAEGGRQNRTGRQQLEYWARIGRAMTAHETASLHRVHEALAGTRELSELTAAEGRLFDAEI
DARLADGLARTDYAEILAARGVTTVVLDDEGRLVEQHPDGSRRVLDDA

Download         Length: 387 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References