Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 1028812..1029324 Replicon chromosome
Accession NZ_LT906447
Organism Staphylococcus piscifermentans strain NCTC13836

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag CKV71_RS04600 Protein ID WP_095104324.1
Coordinates 1029118..1029324 (+) Length 69 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag CKV71_RS04595 Protein ID WP_095104322.1
Coordinates 1028812..1029105 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKV71_RS04570 1024195..1024833 + 639 WP_095104307.1 thiamine phosphate synthase -
CKV71_RS04575 1024923..1025798 + 876 WP_095104308.1 membrane protein insertase YidC -
CKV71_RS04580 1025913..1026425 + 513 WP_095104310.1 GNAT family N-acetyltransferase -
CKV71_RS04585 1026494..1027102 - 609 WP_167376386.1 HD domain-containing protein -
CKV71_RS04590 1027166..1028647 - 1482 WP_095104320.1 cardiolipin synthase -
CKV71_RS04595 1028812..1029105 + 294 WP_095104322.1 copper-sensing transcriptional repressor CsoR Antitoxin
CKV71_RS04600 1029118..1029324 + 207 WP_095104324.1 heavy-metal-associated domain-containing protein Toxin
CKV71_RS04605 1029339..1029548 + 210 WP_095104326.1 copper ion binding protein -
CKV71_RS04610 1029693..1031891 + 2199 WP_095104328.1 heavy metal translocating P-type ATPase -
CKV71_RS04620 1032180..1033397 - 1218 WP_095104332.1 rod shape-determining protein RodA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Heavy metal-associated domain, HMA

(24-65)

Antitoxin

Metal-sensitive transcriptional repressor

(3-95)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7745.60 Da        Isoelectric Point: 4.2088

>T293693 WP_095104324.1 NZ_LT906447:1029118-1029324 [Staphylococcus piscifermentans]
MQNSVIKIDGLETEEAQHKLHQHLSEMTGVSAVQVDMDSNEIRISYETPVNLNNLEKEIYDAGYQILN

Download         Length: 207 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11076.69 Da        Isoelectric Point: 6.4854

>AT293693 WP_095104322.1 NZ_LT906447:1028812-1029105 [Staphylococcus piscifermentans]
MTENDKAHHSEQIKSNLKARLNRIEGQVRAINRMIDEDVYCDDVLTQIRATRSALNSVAVKLLDHHMKGCIMHKVDDGHA
EEAMEELLVTVQKLIKD

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References