Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 713261..713872 Replicon chromosome
Accession NZ_LT906435
Organism Pandoraea sputorum strain NCTC13161

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CKW10_RS03235 Protein ID WP_072633186.1
Coordinates 713261..713563 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A239S9E3
Locus tag CKW10_RS03240 Protein ID WP_039395723.1
Coordinates 713567..713872 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKW10_RS03220 709590..710717 + 1128 WP_039402208.1 porin -
CKW10_RS03225 710824..711873 - 1050 WP_039395719.1 aldo/keto reductase -
CKW10_RS03230 712278..713264 + 987 WP_084103423.1 AraC family transcriptional regulator -
CKW10_RS03235 713261..713563 - 303 WP_072633186.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CKW10_RS03240 713567..713872 - 306 WP_039395723.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CKW10_RS03245 713994..716480 - 2487 WP_095178407.1 DNA ligase D -
CKW10_RS03250 716490..717506 - 1017 WP_039395726.1 Ku protein -
CKW10_RS03255 717679..718209 + 531 Protein_646 hypothetical protein -
CKW10_RS03260 718424..718675 + 252 WP_039395729.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-51)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11583.26 Da        Isoelectric Point: 11.5320

>T293677 WP_072633186.1 NZ_LT906435:c713563-713261 [Pandoraea sputorum]
VKLEWSQHAIQDRSDIYDFVEQRSPNAAIWIDSRINQQLLSLLRFPRAGRPGSIRGTRELVITRTPYIAAYRALPTRIRV
LRIFHNAQMWPGDAPTGPHH

Download         Length: 303 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11114.75 Da        Isoelectric Point: 10.0807

>AT293677 WP_039395723.1 NZ_LT906435:c713872-713567 [Pandoraea sputorum]
MAASALVQARIDPALKERASAVLDKMGLTVSDVVRILLTRIANEGALPFGFAADPDAHDAWVRQKVLEALEDTRPAIAHD
DVESHFAARREATRKRISKKR

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A239S9E3

References