Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 155923..156557 Replicon chromosome
Accession NZ_LT906435
Organism Pandoraea sputorum strain NCTC13161

Toxin (Protein)


Gene name vapC Uniprot ID A0A239S680
Locus tag CKW10_RS00660 Protein ID WP_039394568.1
Coordinates 156138..156557 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CKW10_RS00655 Protein ID WP_150660872.1
Coordinates 155923..156123 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKW10_RS00635 150932..151333 + 402 WP_039394559.1 PaaI family thioesterase -
CKW10_RS00640 151378..152223 + 846 WP_039394562.1 patatin-like phospholipase family protein -
CKW10_RS00645 152308..153318 - 1011 WP_039394564.1 D-2-hydroxyacid dehydrogenase family protein -
CKW10_RS00650 153840..155657 + 1818 WP_095178504.1 phosphoenolpyruvate carboxykinase (GTP) -
CKW10_RS00655 155923..156123 + 201 WP_150660872.1 DNA-binding protein Antitoxin
CKW10_RS00660 156138..156557 + 420 WP_039394568.1 type II toxin-antitoxin system VapC family toxin Toxin
CKW10_RS00665 156581..157213 - 633 WP_039394571.1 response regulator transcription factor -
CKW10_RS00670 157210..158598 - 1389 WP_039394574.1 cache domain-containing protein -
CKW10_RS00675 159029..161095 + 2067 WP_039394577.1 carbon starvation protein A -
CKW10_RS00680 161134..161331 + 198 WP_039394580.1 YbdD/YjiX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15928.45 Da        Isoelectric Point: 10.4402

>T293676 WP_039394568.1 NZ_LT906435:156138-156557 [Pandoraea sputorum]
MYLLDTNVISESRKRGGGDEGVQRFMRMTDRRKAPRFLSVITMGELQRGVKVLRHRNDVRQASLIESWLAQLRLDYANDI
LPVDQEICNVWARMRVPNAAHPIDKLIAATALVHKLIVVTRNVKDFSNTGVEVYNPFQP

Download         Length: 420 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7520.68 Da        Isoelectric Point: 4.4155

>AT293676 WP_150660872.1 NZ_LT906435:155923-156123 [Pandoraea sputorum]
MMLIEGIDEQLMRSIESRAAEGGRTPEEEVLMILDRMARVPRFRSLGEALRAMPNVGLDSDFERIN

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A239S680

Antitoxin

Source ID Structure

References