Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 1083443..1084029 Replicon chromosome
Accession NZ_LT906434
Organism Neisseria zoodegmatis strain NCTC12230

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag CKV66_RS05015 Protein ID WP_085363875.1
Coordinates 1083775..1084029 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag CKV66_RS05010 Protein ID WP_085363876.1
Coordinates 1083443..1083778 (-) Length 112 a.a.

Genomic Context

CKV66_RS04990CKV66_RS05005CKV66_RS04985CKV66_RS04995CKV66_RS05000CKV66_RS05010CKV66_RS05015CKV66_RS05020CKV66_RS05025
Location: 1079955..1080461 (507 bp)
Type: Others
Protein ID: WP_085363878.1
Location: 1082553..1083329 (777 bp)
Type: Others
Protein ID: WP_085363877.1
Location: 1079014..1079793 (780 bp)
Type: Others
Protein ID: WP_085363879.1
Location: 1080920..1081858 (939 bp)
Type: Others
Protein ID: WP_054598759.1
Location: 1081884..1082399 (516 bp)
Type: Others
Protein ID: WP_054598760.1
Location: 1083443..1083778 (336 bp)
Type: Antitoxin
Protein ID: WP_085363876.1
Location: 1083775..1084029 (255 bp)
Type: Toxin
Protein ID: WP_085363875.1
Location: 1084731..1085327 (597 bp)
Type: Others
Protein ID: WP_085363874.1
Location: 1085324..1086535 (1212 bp)
Type: Others
Protein ID: WP_085363873.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CKV66_RS049851079014..1079793-780WP_085363879.116S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA-
CKV66_RS049901079955..1080461+507WP_085363878.1hemerythrin domain-containing protein-
CKV66_RS049951080920..1081858-939WP_054598759.14-hydroxy-3-methylbut-2-enyl diphosphate reductase-
CKV66_RS050001081884..1082399-516WP_054598760.1lipoprotein signal peptidase-
CKV66_RS050051082553..1083329+777WP_085363877.1ferredoxin--NADP reductase-
CKV66_RS050101083443..1083778-336WP_085363876.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
CKV66_RS050151083775..1084029-255WP_085363875.1type II toxin-antitoxin system HicA family toxinToxin
CKV66_RS050201084731..1085327-597WP_085363874.1DUF4276 family protein-
CKV66_RS050251085324..1086535-1212WP_085363873.1AAA family ATPase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(23-75)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9433.94 Da        Isoelectric Point: 10.5624

>T293672 WP_085363875.1 NZ_LT906434:c1084029-1083775 [Neisseria zoodegmatis]
MKKKHQRTLALIFNRPVSGSIKWADIEALFAELGAEIQEREGSRVAVILFGQVKVFHRPHPSLDTDKGAVASVRKWLEEN
GVKP

Download         Length: 255 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12031.44 Da        Isoelectric Point: 5.0956

>AT293672 WP_085363876.1 NZ_LT906434:c1083778-1083443 [Neisseria zoodegmatis]
MNNVMEINGHKAIIQYDPETELLRGEFVGLNGGADFYADNVADLHKEGAASLAVFLDVCKEKGIEPYKQYSGRFNVRISP
ETHAAAAAAAAAQNISLNEWVNRAISQSAHV

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References