Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2839879..2840147 Replicon chromosome
Accession NZ_LT903847
Organism Escherichia coli O127:H6 isolate EPEC1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2840007..2840109 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2839879..2840147 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BQ9550_RS14780 2836432..2837094 - 663 WP_000944249.1 exodeoxyribonuclease X -
BQ9550_RS14785 2837118..2837774 - 657 WP_000011646.1 carbon-nitrogen hydrolase family protein -
BQ9550_RS14790 2837876..2838106 - 231 WP_000916763.1 DNA polymerase III subunit theta -
BQ9550_RS14795 2838245..2838619 + 375 WP_000204700.1 CopC domain-containing protein YobA -
BQ9550_RS14800 2838623..2839495 + 873 WP_000879263.1 copper homeostasis membrane protein CopD -
BQ9550_RS14805 2839508..2839849 + 342 WP_000976470.1 YebY family protein -
- 2839879..2840147 - 269 - - Antitoxin
- 2840007..2840109 + 103 - - Toxin
BQ9550_RS14810 2840244..2840900 + 657 WP_000812706.1 protein-serine/threonine phosphatase -
BQ9550_RS14815 2840901..2841092 - 192 WP_001296140.1 YebW family protein -
BQ9550_RS14820 2841197..2841433 - 237 WP_001295499.1 DUF1480 family protein -
BQ9550_RS14825 2841551..2842990 - 1440 WP_001339709.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T293646 NZ_LT903847:2840007-2840109 [Escherichia coli O127:H6]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT293646 NZ_LT903847:c2840147-2839879 [Escherichia coli O127:H6]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGGGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References