Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 61648..62220 Replicon plasmid 2
Accession NZ_LT900339
Organism Gluconobacter oxydans 621H isolate WT-DSMZ

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag BQ9807_RS13280 Protein ID WP_003618720.1
Coordinates 61648..61977 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID Q5HXX4
Locus tag BQ9807_RS13285 Protein ID WP_003618721.1
Coordinates 61978..62220 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BQ9807_RS13260 57870..58904 - 1035 WP_011251445.1 efflux RND transporter periplasmic adaptor subunit -
BQ9807_RS13265 58901..60343 - 1443 WP_172952938.1 TolC family protein -
BQ9807_RS13270 60336..60986 - 651 WP_010516881.1 cation transporter -
BQ9807_RS13275 61060..61458 + 399 WP_062247646.1 helix-turn-helix domain-containing protein -
BQ9807_RS13280 61648..61977 - 330 WP_003618720.1 endoribonuclease MazF Toxin
BQ9807_RS13285 61978..62220 - 243 WP_003618721.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BQ9807_RS13290 62363..63100 - 738 WP_011251447.1 M48 family metallopeptidase -
BQ9807_RS13295 63103..66399 - 3297 WP_011251448.1 HsdR family type I site-specific deoxyribonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..163187 163187


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 16207.44 Da        Isoelectric Point: 5.5500

>T293636 WP_003618720.1 NZ_LT900339:c61977-61648 [Gluconobacter oxydans 621H]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 330 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 11939.32 Da        Isoelectric Point: 5.5500

>AT293636 WP_003618721.1 NZ_LT900339:c62220-61978 [Gluconobacter oxydans 621H]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
F

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6N3T672

References