Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higB-toxA/Tad-PHA01976
Location 2211262..2211919 Replicon chromosome
Accession NZ_LT900217
Organism Gordonibacter urolithinfaciens strain DSM 27213T

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BN3560_RS14380 Protein ID WP_157780568.1
Coordinates 2211262..2211627 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name toxA Uniprot ID -
Locus tag BN3560_RS09515 Protein ID WP_096227865.1
Coordinates 2211620..2211919 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN3560_RS09490 2206834..2207811 + 978 WP_096227861.1 phosphate ABC transporter permease PstA -
BN3560_RS09495 2207804..2208670 + 867 WP_096227862.1 phosphate ABC transporter ATP-binding protein -
BN3560_RS09500 2208790..2209479 + 690 WP_015539548.1 response regulator transcription factor -
BN3560_RS09505 2209532..2210950 + 1419 WP_096227863.1 two-component sensor histidine kinase -
BN3560_RS14380 2211262..2211627 + 366 WP_157780568.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BN3560_RS09515 2211620..2211919 + 300 WP_096227865.1 helix-turn-helix transcriptional regulator Antitoxin
BN3560_RS09520 2212498..2213847 + 1350 WP_096228652.1 replication-associated recombination protein A -
BN3560_RS09525 2213957..2214646 + 690 Protein_1878 DUF948 domain-containing protein -
BN3560_RS09530 2214737..2216032 + 1296 WP_172623286.1 AI-2E family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(32-111)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-88)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 14508.77 Da        Isoelectric Point: 10.5359

>T293634 WP_157780568.1 NZ_LT900217:2211262-2211627 [Gordonibacter urolithinfaciens]
MYKVELYHDAKGRSELLDTLRKLEDKSSTDKEARTAYLSMLKAISELEGHGTRIGMPTVRHVRGEIWELRPKSQRVFFFF
WKDNTFVLLHSYIKKTQKTPRREIMKAERKKRDWIARHADE

Download         Length: 366 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11179.91 Da        Isoelectric Point: 6.9835

>AT293634 WP_096227865.1 NZ_LT900217:2211620-2211919 [Gordonibacter urolithinfaciens]
MSKNEGCYTFQDYLKEAKLTPAEREEIRLDVELTGRLIEAREARGMTQRDLAEASGLKQPAIARIESHRSVPRVDTLLKL
LVPLGYTLKIVPLEGSDRL

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References