Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 22365..22912 Replicon plasmid 2
Accession NZ_LT882487
Organism Salmonella enterica subsp. enterica serovar Typhi isolate 4714STDY6831631

Toxin (Protein)


Gene name parE Uniprot ID E9LLH3
Locus tag CDZ80_RS24795 Protein ID WP_000969996.1
Coordinates 22365..22646 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A1M1SX19
Locus tag CDZ80_RS24800 Protein ID WP_021546940.1
Coordinates 22643..22912 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDZ80_RS24765 18181..18870 + 690 WP_001764183.1 hypothetical protein -
CDZ80_RS24770 19214..19918 + 705 WP_001067852.1 IS6-like element IS26 family transposase -
CDZ80_RS24780 19973..21523 + 1551 Protein_20 Tn3-like element TnAs1 family transposase -
CDZ80_RS24785 21824..22033 - 210 Protein_21 transposase -
CDZ80_RS25795 22107..22319 - 213 Protein_22 3'-5' exonuclease -
CDZ80_RS24795 22365..22646 - 282 WP_000969996.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CDZ80_RS24800 22643..22912 - 270 WP_021546940.1 hypothetical protein Antitoxin
CDZ80_RS24815 23659..24270 + 612 Protein_25 IS3 family transposase -
CDZ80_RS25530 24302..24481 - 180 WP_012600012.1 hypothetical protein -
CDZ80_RS25535 24705..25022 + 318 WP_032156934.1 hypothetical protein -
CDZ80_RS24825 25091..26017 + 927 WP_000617209.1 WYL domain-containing protein -
CDZ80_RS24830 26027..26626 + 600 WP_001021938.1 DUF1819 family protein -
CDZ80_RS24835 26623..27207 + 585 WP_000645940.1 DUF1788 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..79940 79940


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 13852.62 Da        Isoelectric Point: 5.5500

>T293585 WP_000969996.1 NZ_LT882487:c22646-22365 [Salmonella enterica subsp. enterica serovar Typhi]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Download         Length: 282 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 13263.91 Da        Isoelectric Point: 5.5500

>AT293585 WP_021546940.1 NZ_LT882487:c22912-22643 [Salmonella enterica subsp. enterica serovar Typhi]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFF

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB E9LLH3

Antitoxin

Source ID Structure
AlphaFold DB A0A1M1SX19

References