Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 7510956..7511976 Replicon chromosome
Accession NZ_LT859959
Organism Bradyrhizobium sp. ORS 285

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag BRAD285_RS33815 Protein ID WP_035646931.1
Coordinates 7510956..7511534 (-) Length 193 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag BRAD285_RS33820 Protein ID WP_035646914.1
Coordinates 7511530..7511976 (-) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRAD285_RS33795 7506035..7506358 + 324 WP_006612657.1 phosphoribosyl-ATP diphosphatase -
BRAD285_RS33800 7506392..7507348 + 957 WP_006612656.1 type I pantothenate kinase -
BRAD285_RS33805 7507965..7510205 - 2241 WP_006612655.1 response regulator -
BRAD285_RS33810 7510340..7510819 - 480 WP_035646916.1 hypothetical protein -
BRAD285_RS33815 7510956..7511534 - 579 WP_035646931.1 PIN domain-containing protein Toxin
BRAD285_RS33820 7511530..7511976 - 447 WP_035646914.1 helix-turn-helix domain-containing protein Antitoxin
BRAD285_RS33825 7512156..7513694 - 1539 WP_006612651.1 YifB family Mg chelatase-like AAA ATPase -
BRAD285_RS33830 7513921..7514991 + 1071 WP_006612650.1 DUF2336 domain-containing protein -
BRAD285_RS33835 7515007..7515780 - 774 WP_087877739.1 outer membrane lipoprotein carrier protein LolA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-116)

Antitoxin

Helix-turn-helix domain, group 17

(77-123)


Sequences

Toxin        


Download         Length: 193 a.a.        Molecular weight: 21778.00 Da        Isoelectric Point: 6.3290

>T293584 WP_035646931.1 NZ_LT859959:c7511534-7510956 [Bradyrhizobium sp. ORS 285]
ISNHSRYTVILDACTLYPAPLRDLLMETASMGLFRAKWSDRIHDEWISNLLAKRPDLDLAKLERTRHLMNNAVPDCLVTG
YESIIDALDLPDEDDRHVLAAGIHCGADAIVTFNVKDFPVETLAIHHIEPQHPDEFLVHQFGLNEAAVLNAARRCRLRLK
RNPRDAIQYLLALERCGLPQTVAHLRAYSEVI

Download         Length: 579 bp

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16784.17 Da        Isoelectric Point: 6.6512

>AT293584 WP_035646914.1 NZ_LT859959:c7511976-7511530 [Bradyrhizobium sp. ORS 285]
MSARDLERPITLPSKEDTALAQEASRAIATKQPSELKVRLDDGQELTLPKAATRLIAHLLTEMAQGNAVTIIPIHAVLTT
QEAADYLNVSRPHLVSLLEEKRIPYHKVGTHRRVRFQDLVDYRAAFEKRRREIMEELAAQAEQEDMGY

Download         Length: 447 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References