Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 6104475..6105113 Replicon chromosome
Accession NZ_LT859959
Organism Bradyrhizobium sp. ORS 285

Toxin (Protein)


Gene name PumA Uniprot ID A0A1Y6KML6
Locus tag BRAD285_RS27500 Protein ID WP_006611370.1
Coordinates 6104820..6105113 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1Y6KMC9
Locus tag BRAD285_RS27495 Protein ID WP_006611371.1
Coordinates 6104475..6104816 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRAD285_RS27475 6099499..6100491 - 993 WP_006610362.1 TorF family putative porin -
BRAD285_RS27480 6100918..6101394 - 477 WP_006610361.1 hypothetical protein -
BRAD285_RS27485 6101468..6102790 - 1323 WP_087877672.1 glycolate oxidase subunit GlcF -
BRAD285_RS27490 6102787..6104025 - 1239 WP_006611372.1 FAD-binding protein -
BRAD285_RS27495 6104475..6104816 - 342 WP_006611371.1 putative addiction module antidote protein Antitoxin
BRAD285_RS27500 6104820..6105113 - 294 WP_006611370.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BRAD285_RS27505 6105544..6106446 + 903 WP_006611369.1 Sel1 repeat protein -
BRAD285_RS27510 6106598..6106804 - 207 WP_035645897.1 hypothetical protein -
BRAD285_RS27515 6107998..6109491 - 1494 WP_006611368.1 FAD-binding protein -
BRAD285_RS27520 6109703..6110098 + 396 WP_006611367.1 cytochrome c family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Uncharacterized protein HI1420

(3-88)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10821.45 Da        Isoelectric Point: 10.3096

>T293583 WP_006611370.1 NZ_LT859959:c6105113-6104820 [Bradyrhizobium sp. ORS 285]
MVEIRQTAEFKAWLLGLRDLKAKARIAARIERAANGNLGDSKPVGEGVSEMRIDYGPGYRIYYRQRGDVLVILLCGGDKS
TQQSDIRRAQALAKREA

Download         Length: 294 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 11943.67 Da        Isoelectric Point: 10.4599

>AT293583 WP_006611371.1 NZ_LT859959:c6104816-6104475 [Bradyrhizobium sp. ORS 285]
MATTRFDAAEYLAEPEAQAEFLAAALEDGTADEIRAAINTIARARGMSDLAKATGIRREQLYRALGEDGNPEFATILTVL
RALGVKLTSAPAKGASKAAPKRKTAKKVGRRAA

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6KML6

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6KMC9

References