Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-AbrB
Location 4076448..4077073 Replicon chromosome
Accession NZ_LT859959
Organism Bradyrhizobium sp. ORS 285

Toxin (Protein)


Gene name vapC Uniprot ID A0A1Y6KH19
Locus tag BRAD285_RS18385 Protein ID WP_006611051.1
Coordinates 4076675..4077073 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1Y6KH08
Locus tag BRAD285_RS18380 Protein ID WP_006611050.1
Coordinates 4076448..4076678 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRAD285_RS18350 4071536..4071964 - 429 WP_006611045.1 PaaI family thioesterase -
BRAD285_RS18355 4072035..4072856 + 822 WP_035645698.1 enoyl-CoA hydratase -
BRAD285_RS18360 4072985..4073569 + 585 WP_006611047.1 CoA-binding protein -
BRAD285_RS18365 4073797..4075080 + 1284 WP_006611048.1 O-acetylhomoserine aminocarboxypropyltransferase -
BRAD285_RS18370 4075519..4075713 - 195 WP_035645702.1 hypothetical protein -
BRAD285_RS18375 4076032..4076367 + 336 WP_006611049.1 hypothetical protein -
BRAD285_RS18380 4076448..4076678 + 231 WP_006611050.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BRAD285_RS18385 4076675..4077073 + 399 WP_006611051.1 PIN domain-containing protein Toxin
BRAD285_RS18390 4077641..4078729 - 1089 WP_006611052.1 COX15/CtaA family protein -
BRAD285_RS18395 4078832..4079050 + 219 WP_006611053.1 DUF2842 domain-containing protein -
BRAD285_RS18400 4079065..4080126 - 1062 WP_006611054.1 polysaccharide deacetylase family protein -
BRAD285_RS18405 4080414..4081634 + 1221 WP_006611055.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

SpoVT-AbrB domain

(5-32)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14510.45 Da        Isoelectric Point: 4.7884

>T293581 WP_006611051.1 NZ_LT859959:4076675-4077073 [Bradyrhizobium sp. ORS 285]
VSTFFDSNILVYAYSTDPRRDRAIDVIADGGVISVQVLNEFTNVLRRKQKLDWPTVEAALSSIIFRFPDARPLTVATHTT
AIALARDHGLQFYDALIVASALDADCDTLVSEDLQHGRSFGSLTIVNPFLGL

Download         Length: 399 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8423.76 Da        Isoelectric Point: 4.7730

>AT293581 WP_006611050.1 NZ_LT859959:4076448-4076678 [Bradyrhizobium sp. ORS 285]
MQVIKVDDSLAVLLPKKLVDELGIKEGDDVSVLSLAKDAIAVQKAATRAEFLKQIEPLRFPLPADYKFDRDEANGR

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6KH19

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6KH08

References