Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-AbrB
Location 4076448..4077073 Replicon chromosome
Accession NZ_LT859959
Organism Bradyrhizobium sp. ORS 285

Toxin (Protein)


Gene name vapC Uniprot ID A0A1Y6KH19
Locus tag BRAD285_RS18385 Protein ID WP_006611051.1
Coordinates 4076675..4077073 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1Y6KH08
Locus tag BRAD285_RS18380 Protein ID WP_006611050.1
Coordinates 4076448..4076678 (+) Length 77 a.a.

Genomic Context

BRAD285_RS18355BRAD285_RS18360BRAD285_RS18365BRAD285_RS18375BRAD285_RS18380BRAD285_RS18385BRAD285_RS18395BRAD285_RS18405BRAD285_RS18350BRAD285_RS18370BRAD285_RS18390BRAD285_RS18400
Location: 4072035..4072856 (822 bp)
Type: Others
Protein ID: WP_035645698.1
Location: 4072985..4073569 (585 bp)
Type: Others
Protein ID: WP_006611047.1
Location: 4073797..4075080 (1284 bp)
Type: Others
Protein ID: WP_006611048.1
Location: 4076032..4076367 (336 bp)
Type: Others
Protein ID: WP_006611049.1
Location: 4076448..4076678 (231 bp)
Type: Antitoxin
Protein ID: WP_006611050.1
Location: 4076675..4077073 (399 bp)
Type: Toxin
Protein ID: WP_006611051.1
Location: 4078832..4079050 (219 bp)
Type: Others
Protein ID: WP_006611053.1
Location: 4080414..4081634 (1221 bp)
Type: Others
Protein ID: WP_006611055.1
Location: 4071536..4071964 (429 bp)
Type: Others
Protein ID: WP_006611045.1
Location: 4075519..4075713 (195 bp)
Type: Others
Protein ID: WP_035645702.1
Location: 4077641..4078729 (1089 bp)
Type: Others
Protein ID: WP_006611052.1
Location: 4079065..4080126 (1062 bp)
Type: Others
Protein ID: WP_006611054.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BRAD285_RS183504071536..4071964-429WP_006611045.1PaaI family thioesterase-
BRAD285_RS183554072035..4072856+822WP_035645698.1enoyl-CoA hydratase-
BRAD285_RS183604072985..4073569+585WP_006611047.1CoA-binding protein-
BRAD285_RS183654073797..4075080+1284WP_006611048.1O-acetylhomoserine aminocarboxypropyltransferase-
BRAD285_RS183704075519..4075713-195WP_035645702.1hypothetical protein-
BRAD285_RS183754076032..4076367+336WP_006611049.1hypothetical protein-
BRAD285_RS183804076448..4076678+231WP_006611050.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
BRAD285_RS183854076675..4077073+399WP_006611051.1PIN domain-containing proteinToxin
BRAD285_RS183904077641..4078729-1089WP_006611052.1COX15/CtaA family protein-
BRAD285_RS183954078832..4079050+219WP_006611053.1DUF2842 domain-containing protein-
BRAD285_RS184004079065..4080126-1062WP_006611054.1polysaccharide deacetylase family protein-
BRAD285_RS184054080414..4081634+1221WP_006611055.1GNAT family N-acetyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

SpoVT-AbrB domain

(5-32)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14510.45 Da        Isoelectric Point: 4.7884

>T293581 WP_006611051.1 NZ_LT859959:4076675-4077073 [Bradyrhizobium sp. ORS 285]
VSTFFDSNILVYAYSTDPRRDRAIDVIADGGVISVQVLNEFTNVLRRKQKLDWPTVEAALSSIIFRFPDARPLTVATHTT
AIALARDHGLQFYDALIVASALDADCDTLVSEDLQHGRSFGSLTIVNPFLGL

Download         Length: 399 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8423.76 Da        Isoelectric Point: 4.7730

>AT293581 WP_006611050.1 NZ_LT859959:4076448-4076678 [Bradyrhizobium sp. ORS 285]
MQVIKVDDSLAVLLPKKLVDELGIKEGDDVSVLSLAKDAIAVQKAATRAEFLKQIEPLRFPLPADYKFDRDEANGR

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1Y6KH19

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1Y6KH08

References