293579

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parE_1-relB/RelE(toxin)
Location 2045996..2046471 Replicon chromosome
Accession NZ_LT855380
Organism Pseudomonas viridiflava strain CFBP 1590 isolate E12-5

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag CFBP1590_RS09705 Protein ID WP_080665244.1
Coordinates 2046190..2046471 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A5E7EZR3
Locus tag CFBP1590_RS09700 Protein ID WP_029242986.1
Coordinates 2045996..2046190 (+) Length 65 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP1590_RS09680 2041024..2041503 + 480 WP_058431249.1 ATP-binding protein -
CFBP1590_RS09685 2041572..2043743 - 2172 WP_058431250.1 TonB-dependent siderophore receptor -
CFBP1590_RS09690 2044010..2045251 + 1242 WP_088234920.1 M20/M25/M40 family metallo-hydrolase -
CFBP1590_RS09695 2045349..2045759 + 411 WP_025995307.1 S24 family peptidase -
CFBP1590_RS09700 2045996..2046190 + 195 WP_029242986.1 hypothetical protein Antitoxin
CFBP1590_RS09705 2046190..2046471 + 282 WP_080665244.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFBP1590_RS09715 2046880..2047890 + 1011 WP_088234921.1 tRNA dihydrouridine(20/20a) synthase DusA -
CFBP1590_RS09720 2048036..2048467 + 432 WP_025995310.1 universal stress protein -
CFBP1590_RS09725 2048476..2048940 - 465 WP_004881182.1 response regulator -
CFBP1590_RS09730 2048937..2051264 - 2328 WP_088234922.1 PAS domain S-box protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-90)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 10517.27 Da        Isoelectric Point: 9.8796

>T293579 WP_080665244.1 NZ_LT855380:2046190-2046471 [Pseudomonas viridiflava]
MLPIVWLQAAVNDLSSIILYISNENPSAARRLKSRLQAAPLPLVEHPYLFPLGRVSGTRELVAHPNYIIVYRIASDRVEI
VNVLHSRQTYPLT

Download         Length: 282 bp


Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7095.90 Da        Isoelectric Point: 4.1947

>AT293579 WP_029242986.1 NZ_LT855380:2045996-2046190 [Pseudomonas viridiflava]
MSTTLSPIVSEFDTQEQADSYDLWFRAKVEASLAEPGRAVPHDEVMARMDAIIEAAEARQRLGS

Download         Length: 195 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A5E7EZR3

References