Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 1318768..1319466 Replicon chromosome
Accession NZ_LT855380
Organism Pseudomonas viridiflava strain CFBP 1590 isolate E12-5

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag CFBP1590_RS06255 Protein ID WP_004881256.1
Coordinates 1319284..1319466 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID A0A5E6SCC0
Locus tag CFBP1590_RS06250 Protein ID WP_025996829.1
Coordinates 1318768..1319178 (-) Length 137 a.a.

Genomic Context

CFBP1590_RS06230CFBP1590_RS06235CFBP1590_RS06245CFBP1590_RS06265CFBP1590_RS06240CFBP1590_RS06250CFBP1590_RS06255CFBP1590_RS06260
Location: 1314548..1315717 (1170 bp)
Type: Others
Protein ID: WP_004881265.1
Location: 1315795..1317111 (1317 bp)
Type: Others
Protein ID: WP_088234668.1
Location: 1317551..1318642 (1092 bp)
Type: Others
Protein ID: WP_088234669.1
Location: 1323095..1323595 (501 bp)
Type: Others
Protein ID: WP_069144671.1
Location: 1317162..1317473 (312 bp)
Type: Others
Protein ID: WP_167383111.1
Location: 1318768..1319178 (411 bp)
Type: Antitoxin
Protein ID: WP_025996829.1
Location: 1319284..1319466 (183 bp)
Type: Toxin
Protein ID: WP_004881256.1
Location: 1319752..1322688 (2937 bp)
Type: Others
Protein ID: WP_167383112.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CFBP1590_RS062301314548..1315717+1170WP_004881265.1mandelate racemase/muconate lactonizing enzyme family protein-
CFBP1590_RS062351315795..1317111+1317WP_088234668.1C4-dicarboxylate transporter DctA-
CFBP1590_RS062401317162..1317473-312WP_167383111.1helix-turn-helix domain-containing protein-
CFBP1590_RS062451317551..1318642+1092WP_088234669.1NADH:flavin oxidoreductase/NADH oxidase-
CFBP1590_RS062501318768..1319178-411WP_025996829.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
CFBP1590_RS062551319284..1319466-183WP_004881256.1type II toxin-antitoxin system HicA family toxinToxin
CFBP1590_RS062601319752..1322688-2937WP_167383112.1autotransporter domain-containing protein-
CFBP1590_RS062651323095..1323595+501WP_069144671.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-127)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6888.95 Da        Isoelectric Point: 10.5417

>T293578 WP_004881256.1 NZ_LT855380:c1319466-1319284 [Pseudomonas viridiflava]
MRSREMIRTIEDDGWYLVATKGSHHQYKHSSKPGRVTIKHPDSDIPIKTMNSILKQAGLK

Download         Length: 183 bp

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 14851.63 Da        Isoelectric Point: 4.6312

>AT293578 WP_025996829.1 NZ_LT855380:c1319178-1318768 [Pseudomonas viridiflava]
MKFTVVLHKDADSDYGVTVPDVPGCFSAGSSVSEALESVKEALSLHFEGLVADGAPLPNAQAIDIHMANPDYEDGIWAVV
EFDVTPYFGKSVRFNATLPEHLLAKIDERVKTDHRYASRSGFLAAAALNELHTEYR

Download         Length: 411 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A5E6SCC0

References