Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 584530..585141 Replicon chromosome
Accession NZ_LT855380
Organism Pseudomonas viridiflava strain CFBP 1590 isolate E12-5

Toxin (Protein)


Gene name PfiT Uniprot ID Q4ZME8
Locus tag CFBP1590_RS02815 Protein ID WP_003304103.1
Coordinates 584791..585141 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID Q4ZME7
Locus tag CFBP1590_RS02810 Protein ID WP_002556076.1
Coordinates 584530..584778 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP1590_RS02785 579764..580660 + 897 WP_017709553.1 LysR family transcriptional regulator -
CFBP1590_RS02790 580818..581810 + 993 WP_017709554.1 YncE family protein -
CFBP1590_RS02795 582135..582515 + 381 WP_010924793.1 hypothetical protein -
CFBP1590_RS02800 582996..583202 + 207 WP_161806366.1 hypothetical protein -
CFBP1590_RS02805 583231..584193 - 963 WP_010924794.1 tyrosine-type recombinase/integrase -
CFBP1590_RS02810 584530..584778 + 249 WP_002556076.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CFBP1590_RS02815 584791..585141 + 351 WP_003304103.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFBP1590_RS02825 585793..587178 - 1386 WP_103365183.1 P-type conjugative transfer protein TrbL -
CFBP1590_RS02830 587382..588137 - 756 WP_088234448.1 P-type conjugative transfer protein TrbJ -
CFBP1590_RS02835 588178..588552 - 375 WP_088234449.1 conjugal transfer transcriptional regulator TraJ -
CFBP1590_RS02840 588845..589123 - 279 WP_088234450.1 conjugal transfer protein TraK -
CFBP1590_RS02845 589190..589915 - 726 WP_088236353.1 phage replication protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 564726..591629 26903


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-98)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12973.76 Da        Isoelectric Point: 4.7690

>T293577 WP_003304103.1 NZ_LT855380:584791-585141 [Pseudomonas viridiflava]
MNTFALRFTDVAQQSLEDQVEHLAVHQGFSSAAQRIDTLIDAIQDKLLSTPLGYPVSHQLSELGVLHYRELNTDGYRIFY
EVRDAGDINVIVVALVLGSKQSVEQALIRYCLLQAI

Download         Length: 351 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9366.73 Da        Isoelectric Point: 9.9579

>AT293577 WP_002556076.1 NZ_LT855380:584530-584778 [Pseudomonas viridiflava]
MRVETISFLKRNAADLPLDEPLVVTQNGVPAYVVESYADRKRRDESIALVKLLAISSREYSQGKHCSTDELKARLSRRFT
QK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9GDS9

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9GM89

References