Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 1376589..1377114 Replicon chromosome
Accession NZ_LT854705
Organism Levilactobacillus zymae strain ACA-DC 3411

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag LZ3411_RS06440 Protein ID WP_087742015.1
Coordinates 1376857..1377114 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag LZ3411_RS06435 Protein ID WP_087742014.1
Coordinates 1376589..1376855 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ3411_RS06405 1371713..1372567 - 855 WP_087742008.1 aldo/keto reductase -
LZ3411_RS06410 1372585..1373187 - 603 WP_087742009.1 NAD(P)H-binding protein -
LZ3411_RS06415 1373189..1373632 - 444 WP_087742010.1 nuclear transport factor 2 family protein -
LZ3411_RS06420 1373753..1375207 - 1455 WP_087742011.1 MFS transporter -
LZ3411_RS06425 1375221..1375598 - 378 WP_087742012.1 nuclear transport factor 2 family protein -
LZ3411_RS06430 1375779..1376363 - 585 WP_087742013.1 TetR/AcrR family transcriptional regulator -
LZ3411_RS06435 1376589..1376855 + 267 WP_087742014.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LZ3411_RS06440 1376857..1377114 + 258 WP_087742015.1 Txe/YoeB family addiction module toxin Toxin
LZ3411_RS06445 1377227..1378054 - 828 WP_087742016.1 NmrA family NAD(P)-binding protein -
LZ3411_RS06450 1378186..1378743 + 558 WP_087742017.1 TetR/AcrR family transcriptional regulator C-terminal domain-containing protein -
LZ3411_RS06455 1378815..1379345 - 531 WP_087742018.1 serine hydrolase -
LZ3411_RS06460 1379345..1380226 - 882 WP_087742019.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10391.72 Da        Isoelectric Point: 9.4545

>T293574 WP_087742015.1 NZ_LT854705:1376857-1377114 [Levilactobacillus zymae]
MGIYWSDDAWQDYRYWQDQGDKKKLRKINALIKDITRHPFSGQGKPEPLKHELTGKWSRRITGEYRLIYRIEDDALYLYS
ARDYY

Download         Length: 258 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10023.24 Da        Isoelectric Point: 4.4906

>AT293574 WP_087742014.1 NZ_LT854705:1376589-1376855 [Levilactobacillus zymae]
MDAVNYTNFRQNLKSFMKTVNEDSEPLIVTTKKGEDDVVVLSKDDYDAMTETMRILSNQPLMDKIRRGDAQFAKGQGKQH
ALIDPEDD

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References