Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 16983..17533 Replicon plasmid pPD5205-21
Accession NZ_LT853887
Organism Xanthomonas fragariae strain PD5205

Toxin (Protein)


Gene name parE Uniprot ID A0A1Y6HCU7
Locus tag PD5205_RS20065 Protein ID WP_002804295.1
Coordinates 16983..17267 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1Y6HDJ6
Locus tag PD5205_RS20070 Protein ID WP_002804296.1
Coordinates 17255..17533 (-) Length 93 a.a.

Genomic Context

PD5205_RS21080PD5205_RS21545PD5205_RS20045PD5205_RS20050PD5205_RS20055PD5205_RS20060PD5205_RS21650PD5205_RS20080PD5205_RS21550PD5205_RS20085PD5205_RS20090PD5205_RS20095PD5205_RS20040PD5205_RS20065PD5205_RS20070
Location: 13042..13485 (444 bp)
Type: Others
Protein ID: WP_145954081.1
Location: 13492..13656 (165 bp)
Type: Others
Protein ID: WP_156775378.1
Location: 13844..14419 (576 bp)
Type: Others
Protein ID: WP_040762337.1
Location: 14430..14696 (267 bp)
Type: Others
Protein ID: WP_002804333.1
Location: 14831..16546 (1716 bp)
Type: Others
Protein ID: WP_083215115.1
Location: 16615..16797 (183 bp)
Type: Others
Protein ID: WP_134656646.1
Location: 17817..18365 (549 bp)
Type: Others
Protein ID: WP_002804297.1
Location: 18355..19002 (648 bp)
Type: Others
Protein ID: WP_002804298.1
Location: 18999..19136 (138 bp)
Type: Others
Protein ID: WP_167699514.1
Location: 19246..19865 (620 bp)
Type: Others
Protein ID: Protein_31
Location: 19869..20231 (363 bp)
Type: Others
Protein ID: WP_002804300.1
Location: 20314..20637 (324 bp)
Type: Others
Protein ID: WP_002804301.1
Location: 12589..12990 (402 bp)
Type: Others
Protein ID: WP_002804331.1
Location: 16983..17267 (285 bp)
Type: Toxin
Protein ID: WP_002804295.1
Location: 17255..17533 (279 bp)
Type: Antitoxin
Protein ID: WP_002804296.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PD5205_RS2004012589..12990-402WP_002804331.1hypothetical protein-
PD5205_RS2108013042..13485+444WP_145954081.1hypothetical protein-
PD5205_RS2154513492..13656+165WP_156775378.1hypothetical protein-
PD5205_RS2004513844..14419+576WP_040762337.1recombinase family protein-
PD5205_RS2005014430..14696+267WP_002804333.1hypothetical protein-
PD5205_RS2005514831..16546+1716WP_083215115.1AAA family ATPase-
PD5205_RS2006016615..16797+183WP_134656646.1hypothetical protein-
PD5205_RS2006516983..17267-285WP_002804295.1type II toxin-antitoxin system RelE/ParE family toxinToxin
PD5205_RS2007017255..17533-279WP_002804296.1CopG family ribbon-helix-helix proteinAntitoxin
PD5205_RS2165017817..18365+549WP_002804297.1hypothetical protein-
PD5205_RS2008018355..19002+648WP_002804298.1recombinase family protein-
PD5205_RS2155018999..19136+138WP_167699514.1hypothetical protein-
PD5205_RS2008519246..19865+620Protein_31ParA family protein-
PD5205_RS2009019869..20231+363WP_002804300.1hypothetical protein-
PD5205_RS2009520314..20637+324WP_002804301.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..2083020830
-flankIS/Tn--13805..14419614


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-93)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10801.49 Da        Isoelectric Point: 10.0858

>T293573 WP_002804295.1 NZ_LT853887:c17267-16983 [Xanthomonas fragariae]
VPHLIWTPPALADVQRLYRFLAPKDADAARRAVQAIRAQVKILAHQPRIGRPVEDMAPEFRDWLIDFGDSGYVARYRINE
NMVTILAVRHQKEA

Download         Length: 285 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10760.05 Da        Isoelectric Point: 5.1991

>AT293573 WP_002804296.1 NZ_LT853887:c17533-17255 [Xanthomonas fragariae]
MASPTSLKLDDELKGRVQHLAQTQRRTPHWIMREAIAQYVEREEKRETFKQDALRAWEDYQRTGLHLTLEETDAWLAKLE
AGEDAELPACHT

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1Y6HCU7

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1Y6HDJ6

References