Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 11238..11817 Replicon plasmid pPD5205-30
Accession NZ_LT853886
Organism Xanthomonas fragariae strain PD5205

Toxin (Protein)


Gene name relE Uniprot ID A0A1Y6HD38
Locus tag PD5205_RS19815 Protein ID WP_002805372.1
Coordinates 11238..11531 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1Y6HUN4
Locus tag PD5205_RS19820 Protein ID WP_002805369.1
Coordinates 11518..11817 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PD5205_RS19780 6472..7023 + 552 WP_065975505.1 plasmid mobilization relaxosome protein MobC -
PD5205_RS19785 7010..8029 + 1020 WP_052032118.1 relaxase/mobilization nuclease domain-containing protein -
PD5205_RS19795 8687..9286 + 600 WP_065975504.1 hypothetical protein -
PD5205_RS19805 9790..10542 - 753 WP_065975503.1 hypothetical protein -
PD5205_RS19810 10763..10987 + 225 WP_002805375.1 hypothetical protein -
PD5205_RS21525 10984..11160 - 177 WP_156775376.1 hypothetical protein -
PD5205_RS19815 11238..11531 - 294 WP_002805372.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PD5205_RS19820 11518..11817 - 300 WP_002805369.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PD5205_RS19830 12296..12721 + 426 WP_167699513.1 antitoxin VbhA family protein -
PD5205_RS19835 12763..13338 + 576 WP_065975506.1 recombinase family protein -
PD5205_RS19840 13499..13768 - 270 WP_052032117.1 DUF3717 domain-containing protein -
PD5205_RS19845 13765..14388 - 624 WP_002805358.1 transglycosylase SLT domain-containing protein -
PD5205_RS19850 14385..16229 - 1845 WP_065975501.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..30469 30469


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-55)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10915.49 Da        Isoelectric Point: 5.1409

>T293572 WP_002805372.1 NZ_LT853886:c11531-11238 [Xanthomonas fragariae]
VLVLEWRETARADLLAIVDYISDDNPDAAQRLKDDIEAKASMLPERPKLYRPGRVAGTREMVVRSNYVVVYAEDARAVSI
LRVLHAAQQWPPVTGVE

Download         Length: 294 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10717.25 Da        Isoelectric Point: 8.9086

>AT293572 WP_002805369.1 NZ_LT853886:c11817-11518 [Xanthomonas fragariae]
MAAHTSMLHIRVDDALKAQAAETLANVGLTVSDAVRILLTRVAKEGGLPAGLTADPEAHDAWFRGKVQEALADTRPAVPH
RQVMDEAQALIDRKRRARS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HD38

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6HUN4

References