Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2004008..2004678 Replicon chromosome
Accession NZ_LT853885
Organism Xanthomonas fragariae strain PD5205

Toxin (Protein)


Gene name vapC Uniprot ID A0A1Y6H9H7
Locus tag PD5205_RS09425 Protein ID WP_002805728.1
Coordinates 2004259..2004678 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1Y6HLT7
Locus tag PD5205_RS09420 Protein ID WP_002805732.1
Coordinates 2004008..2004262 (+) Length 85 a.a.

Genomic Context

PD5205_RS09400PD5205_RS09405PD5205_RS09410PD5205_RS09415PD5205_RS09420PD5205_RS09425PD5205_RS09430PD5205_RS09435PD5205_RS09440PD5205_RS09445PD5205_RS09395
Location: 2000679..2000912 (234 bp)
Type: Others
Protein ID: WP_002805742.1
Location: 2000916..2001794 (879 bp)
Type: Others
Protein ID: WP_002805739.1
Location: 2001766..2002653 (888 bp)
Type: Others
Protein ID: WP_172404498.1
Location: 2003315..2003596 (282 bp)
Type: Others
Protein ID: WP_002805735.1
Location: 2004008..2004262 (255 bp)
Type: Antitoxin
Protein ID: WP_002805732.1
Location: 2004259..2004678 (420 bp)
Type: Toxin
Protein ID: WP_002805728.1
Location: 2004835..2005449 (615 bp)
Type: Others
Protein ID: WP_040762517.1
Location: 2005535..2005777 (243 bp)
Type: Others
Protein ID: Protein_1833
Location: 2005895..2007262 (1368 bp)
Type: Others
Protein ID: WP_065975195.1
Location: 2007285..2008190 (906 bp)
Type: Others
Protein ID: Protein_1835
Location: 1999593..2000597 (1005 bp)
Type: Others
Protein ID: WP_002805744.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PD5205_RS093951999593..2000597-1005WP_002805744.1hypothetical protein-
PD5205_RS094002000679..2000912+234WP_002805742.1hypothetical protein-
PD5205_RS094052000916..2001794+879WP_002805739.1helicase RepA family protein-
PD5205_RS094102001766..2002653+888WP_172404498.1replication protein C-
PD5205_RS094152003315..2003596+282WP_002805735.1TraK family protein-
PD5205_RS094202004008..2004262+255WP_002805732.1Arc family DNA-binding proteinAntitoxin
PD5205_RS094252004259..2004678+420WP_002805728.1type II toxin-antitoxin system VapC family toxinToxin
PD5205_RS094302004835..2005449+615WP_040762517.1P-type conjugative transfer protein TrbJ-
PD5205_RS094352005535..2005777+243Protein_1833transposase-
PD5205_RS094402005895..2007262+1368WP_065975195.1IS5 family transposase-
PD5205_RS094452007285..2008190+906Protein_1835IS3 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--1989322..200695817636
-flankIS/Tn--1998182..19995191337


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14879.07 Da        Isoelectric Point: 5.1890

>T293570 WP_002805728.1 NZ_LT853885:2004259-2004678 [Xanthomonas fragariae]
MIVLDTNVVSEAIKPEPNPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFGERVLMFDTE
AARHYAELAVKARTAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHQ

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9522.89 Da        Isoelectric Point: 5.7425

>AT293570 WP_002805732.1 NZ_LT853885:2004008-2004262 [Xanthomonas fragariae]
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSEKRIRMGDALAELGRQVVLTNDDFAVLDQVRDKVPAEP
MRFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1Y6H9H7

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1Y6HLT7

References