Detailed information of TA system TA029357

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 1403952..1404703
• Replicon: chromosome
• Accession: NC_021066
• Organism: Raoultella ornithinolytica B6

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: RORB6_RS06305
• Protein ID: WP_015584327.1
• Coordinates: 1404221..1404703 (+)
• Length: 161 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: A0A808Y4Y8
• Locus tag: RORB6_RS06300
• Protein ID: WP_015584326.1
• Coordinates: 1403952..1404230 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RORB6_RS06285	1399147..1400514	+	1368	Protein_1247	KUP/HAK/KT family potassium transporter	-
RORB6_RS06290	1400730..1401227	+	498	WP_048023692.1	hypothetical protein	-
RORB6_RS06295	1401385..1403310	-	1926	WP_015584325.1	C1 family peptidase	-
RORB6_RS06300	1403952..1404230	+	279	WP_015584326.1	DUF1778 domain-containing protein	Antitoxin
RORB6_RS06305	1404221..1404703	+	483	WP_015584327.1	GNAT family N-acetyltransferase	Toxin
RORB6_RS26370	1405044..1405229	+	186	WP_015584328.1	hypothetical protein	-
RORB6_RS26375	1405335..1405496	-	162	WP_155075028.1	hypothetical protein	-
RORB6_RS06310	1406214..1407089	-	876	WP_015584329.1	NAD(P)-dependent oxidoreductase	-
RORB6_RS06315	1407351..1408067	-	717	WP_015584330.1	ABC transporter ATP-binding protein	-
RORB6_RS06320	1408064..1408939	-	876	WP_015584331.1	ATP-binding cassette domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (45-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (3-92)

Sequences

Toxin

Protein

• Length: 161 a.a.
• Molecular weight: 17670.56 Da
• Isoelectric Point: 9.7381

>T29357 WP_015584327.1 NC_021066:1404221-1404703 [Raoultella ornithinolytica B6]
MGMRPPEPLSTGHNIAEFCCQDQVLNEWLKKKALKNHSTGISRVFVVCAENTKRVIAYYSLSSGSVHRNTVPGAYRRNAP
EAVPVIVLGRLAVDAAWVGKGLGAALLKDAIYRTEHIAVQVGVRALLVHALNDEVREFYTRFGFEPSIINTLTLLFPIKV

Nucleotide

• Length: 483 bp

>T29357 NC_021066:1404221-1404703 [Raoultella ornithinolytica B6]
ATGGGAATGAGACCACCGGAACCACTCAGCACTGGACACAACATAGCAGAATTTTGTTGTCAGGATCAGGTTCTTAACGA
GTGGTTGAAGAAGAAGGCGCTGAAGAACCACAGTACAGGCATTTCAAGGGTCTTTGTGGTCTGTGCCGAAAACACAAAAA
GGGTCATCGCGTATTACAGCTTGTCATCCGGGAGCGTGCACAGAAACACAGTACCGGGGGCATACCGTCGTAATGCACCT
GAAGCTGTACCGGTCATTGTTCTGGGAAGGCTTGCGGTCGATGCAGCCTGGGTAGGGAAGGGACTCGGAGCGGCACTGCT
TAAGGATGCAATATACCGTACAGAACATATCGCAGTTCAGGTCGGTGTAAGGGCGCTTCTCGTCCATGCCTTGAATGATG
AAGTCAGGGAGTTTTACACCAGGTTTGGATTCGAGCCCTCGATTATCAATACACTGACATTATTGTTCCCGATAAAAGTA
TGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10714.30 Da
• Isoelectric Point: 4.6722

>AT29357 WP_015584326.1 NC_021066:1403952-1404230 [Raoultella ornithinolytica B6]
MKPDVREAPINIRAKTSQRDLIDMAANLVSKSRTDFMLEVACREAQDILLDQRLFLLDDKQFASFMEELDAPMTAERQAR
IDNLMNRKSPWE

Nucleotide

• Length: 279 bp

>AT29357 NC_021066:1403952-1404230 [Raoultella ornithinolytica B6]
ATGAAACCAGACGTTCGTGAAGCTCCGATAAACATTCGGGCGAAAACATCCCAGCGCGACCTTATCGACATGGCCGCAAA
TCTTGTATCTAAATCACGTACTGATTTTATGCTTGAAGTGGCCTGTCGCGAAGCTCAGGACATTCTGTTGGATCAGCGCT
TGTTCCTGCTGGACGATAAGCAGTTTGCTAGTTTCATGGAAGAGCTTGACGCACCTATGACAGCGGAGCGTCAGGCACGT
ATTGATAACCTGATGAACCGCAAATCGCCATGGGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A808Y4Y8