Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 10001..10580 Replicon plasmid pPD885-29
Accession NZ_LT853883
Organism Xanthomonas fragariae strain PD885

Toxin (Protein)


Gene name relE Uniprot ID A0A1Y6HD38
Locus tag PD885_RS19910 Protein ID WP_002805372.1
Coordinates 10001..10294 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1Y6HUN4
Locus tag PD885_RS19915 Protein ID WP_002805369.1
Coordinates 10281..10580 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PD885_RS19875 5235..5786 + 552 WP_065975505.1 plasmid mobilization relaxosome protein MobC -
PD885_RS19880 5773..6792 + 1020 WP_052032118.1 relaxase/mobilization nuclease domain-containing protein -
PD885_RS19890 7450..8049 + 600 WP_065975504.1 hypothetical protein -
PD885_RS19900 8553..9305 - 753 WP_065975503.1 hypothetical protein -
PD885_RS19905 9526..9750 + 225 WP_002805375.1 hypothetical protein -
PD885_RS21650 9747..9923 - 177 WP_156775376.1 hypothetical protein -
PD885_RS19910 10001..10294 - 294 WP_002805372.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PD885_RS19915 10281..10580 - 300 WP_002805369.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PD885_RS19925 11059..11484 + 426 WP_167699513.1 antitoxin VbhA family protein -
PD885_RS19930 11526..12101 + 576 WP_065975506.1 recombinase family protein -
PD885_RS19935 12262..12486 - 225 WP_002805360.1 DUF3717 domain-containing protein -
PD885_RS19940 12528..13151 - 624 WP_002805358.1 transglycosylase SLT domain-containing protein -
PD885_RS19945 13148..14992 - 1845 WP_065975501.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..29233 29233


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-55)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10915.49 Da        Isoelectric Point: 5.1409

>T293566 WP_002805372.1 NZ_LT853883:c10294-10001 [Xanthomonas fragariae]
VLVLEWRETARADLLAIVDYISDDNPDAAQRLKDDIEAKASMLPERPKLYRPGRVAGTREMVVRSNYVVVYAEDARAVSI
LRVLHAAQQWPPVTGVE

Download         Length: 294 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10717.25 Da        Isoelectric Point: 8.9086

>AT293566 WP_002805369.1 NZ_LT853883:c10580-10281 [Xanthomonas fragariae]
MAAHTSMLHIRVDDALKAQAAETLANVGLTVSDAVRILLTRVAKEGGLPAGLTADPEAHDAWFRGKVQEALADTRPAVPH
RQVMDEAQALIDRKRRARS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HD38

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6HUN4

References