Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 10001..10580 Replicon plasmid pPD885-29
Accession NZ_LT853883
Organism Xanthomonas fragariae strain PD885

Toxin (Protein)


Gene name relE Uniprot ID A0A1Y6HD38
Locus tag PD885_RS19910 Protein ID WP_002805372.1
Coordinates 10001..10294 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1Y6HUN4
Locus tag PD885_RS19915 Protein ID WP_002805369.1
Coordinates 10281..10580 (-) Length 100 a.a.

Genomic Context

PD885_RS19875PD885_RS19880PD885_RS19890PD885_RS19905PD885_RS19925PD885_RS19930PD885_RS19900PD885_RS21650PD885_RS19910PD885_RS19915PD885_RS19935PD885_RS19940PD885_RS19945
Location: 5235..5786 (552 bp)
Type: Others
Protein ID: WP_065975505.1
Location: 5773..6792 (1020 bp)
Type: Others
Protein ID: WP_052032118.1
Location: 7450..8049 (600 bp)
Type: Others
Protein ID: WP_065975504.1
Location: 9526..9750 (225 bp)
Type: Others
Protein ID: WP_002805375.1
Location: 11059..11484 (426 bp)
Type: Others
Protein ID: WP_167699513.1
Location: 11526..12101 (576 bp)
Type: Others
Protein ID: WP_065975506.1
Location: 8553..9305 (753 bp)
Type: Others
Protein ID: WP_065975503.1
Location: 9747..9923 (177 bp)
Type: Others
Protein ID: WP_156775376.1
Location: 10001..10294 (294 bp)
Type: Toxin
Protein ID: WP_002805372.1
Location: 10281..10580 (300 bp)
Type: Antitoxin
Protein ID: WP_002805369.1
Location: 12262..12486 (225 bp)
Type: Others
Protein ID: WP_002805360.1
Location: 12528..13151 (624 bp)
Type: Others
Protein ID: WP_002805358.1
Location: 13148..14992 (1845 bp)
Type: Others
Protein ID: WP_065975501.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PD885_RS198755235..5786+552WP_065975505.1plasmid mobilization relaxosome protein MobC-
PD885_RS198805773..6792+1020WP_052032118.1relaxase/mobilization nuclease domain-containing protein-
PD885_RS198907450..8049+600WP_065975504.1hypothetical protein-
PD885_RS199008553..9305-753WP_065975503.1hypothetical protein-
PD885_RS199059526..9750+225WP_002805375.1hypothetical protein-
PD885_RS216509747..9923-177WP_156775376.1hypothetical protein-
PD885_RS1991010001..10294-294WP_002805372.1type II toxin-antitoxin system RelE/ParE family toxinToxin
PD885_RS1991510281..10580-300WP_002805369.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
PD885_RS1992511059..11484+426WP_167699513.1antitoxin VbhA family protein-
PD885_RS1993011526..12101+576WP_065975506.1recombinase family protein-
PD885_RS1993512262..12486-225WP_002805360.1DUF3717 domain-containing protein-
PD885_RS1994012528..13151-624WP_002805358.1transglycosylase SLT domain-containing protein-
PD885_RS1994513148..14992-1845WP_065975501.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..2923329233


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-55)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10915.49 Da        Isoelectric Point: 5.1409

>T293566 WP_002805372.1 NZ_LT853883:c10294-10001 [Xanthomonas fragariae]
VLVLEWRETARADLLAIVDYISDDNPDAAQRLKDDIEAKASMLPERPKLYRPGRVAGTREMVVRSNYVVVYAEDARAVSI
LRVLHAAQQWPPVTGVE

Download         Length: 294 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10717.25 Da        Isoelectric Point: 8.9086

>AT293566 WP_002805369.1 NZ_LT853883:c10580-10281 [Xanthomonas fragariae]
MAAHTSMLHIRVDDALKAQAAETLANVGLTVSDAVRILLTRVAKEGGLPAGLTADPEAHDAWFRGKVQEALADTRPAVPH
RQVMDEAQALIDRKRRARS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1Y6HD38

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1Y6HUN4

References