Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 17193..17752 Replicon plasmid pNBC2815-21
Accession NZ_LT853881
Organism Xanthomonas fragariae strain NBC2815

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NBC2815_RS19840 Protein ID WP_088062711.1
Coordinates 17193..17486 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1Y6HDJ6
Locus tag NBC2815_RS19845 Protein ID WP_002804296.1
Coordinates 17474..17752 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBC2815_RS19815 12787..13188 - 402 WP_088062707.1 hypothetical protein -
NBC2815_RS20770 13240..13683 + 444 WP_134656644.1 hypothetical protein -
NBC2815_RS21095 13690..13854 + 165 WP_156775378.1 hypothetical protein -
NBC2815_RS19820 14042..14617 + 576 WP_040762337.1 recombinase family protein -
NBC2815_RS19825 14628..14894 + 267 WP_002804333.1 hypothetical protein -
NBC2815_RS19830 15040..16725 + 1686 WP_088062709.1 AAA family ATPase -
NBC2815_RS19835 16834..17016 + 183 WP_134656646.1 hypothetical protein -
NBC2815_RS19840 17193..17486 - 294 WP_088062711.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NBC2815_RS19845 17474..17752 - 279 WP_002804296.1 CopG family ribbon-helix-helix protein Antitoxin
NBC2815_RS21200 18030..18578 + 549 WP_002804297.1 hypothetical protein -
NBC2815_RS19855 18568..19215 + 648 WP_002804298.1 recombinase family protein -
NBC2815_RS21100 19212..19349 + 138 WP_167699514.1 hypothetical protein -
NBC2815_RS19860 19459..20091 + 633 WP_002804299.1 ParA family protein -
NBC2815_RS19865 20084..20446 + 363 WP_002804300.1 hypothetical protein -
NBC2815_RS19870 20529..20852 + 324 WP_002804301.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..21045 21045
- flank IS/Tn - - 14003..14617 614


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11102.84 Da        Isoelectric Point: 10.0858

>T293562 WP_088062711.1 NZ_LT853881:c17486-17193 [Xanthomonas fragariae]
VPHLIWTPPALADVQRLYRFLAPKDADAARRAVQAIRAQVKILAHQPRIGRPVEDMAPEFRDWLIDFGDSGYVARYRINE
NMVTILAVRHQKEAGFP

Download         Length: 294 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10760.05 Da        Isoelectric Point: 5.1991

>AT293562 WP_002804296.1 NZ_LT853881:c17752-17474 [Xanthomonas fragariae]
MASPTSLKLDDELKGRVQHLAQTQRRTPHWIMREAIAQYVEREEKRETFKQDALRAWEDYQRTGLHLTLEETDAWLAKLE
AGEDAELPACHT

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6HDJ6

References