Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2287012..2287682 Replicon chromosome
Accession NZ_LT853880
Organism Xanthomonas fragariae strain NBC2815

Toxin (Protein)


Gene name vapC Uniprot ID A0A1Y6H9H7
Locus tag NBC2815_RS10415 Protein ID WP_002805728.1
Coordinates 2287012..2287431 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1Y6HLT7
Locus tag NBC2815_RS10420 Protein ID WP_002805732.1
Coordinates 2287428..2287682 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBC2815_RS20360 2282174..2283046 + 873 WP_145953987.1 hypothetical protein -
NBC2815_RS10400 2283417..2284784 + 1368 WP_088062542.1 IS5 family transposase -
NBC2815_RS10410 2286130..2286855 - 726 WP_088062544.1 P-type conjugative transfer protein TrbJ -
NBC2815_RS10415 2287012..2287431 - 420 WP_002805728.1 type II toxin-antitoxin system VapC family toxin Toxin
NBC2815_RS10420 2287428..2287682 - 255 WP_002805732.1 Arc family DNA-binding protein Antitoxin
NBC2815_RS10425 2288094..2288375 - 282 WP_002805735.1 TraK family protein -
NBC2815_RS10430 2288993..2289566 - 574 Protein_1995 hypothetical protein -
NBC2815_RS10435 2289538..2290416 - 879 WP_002805739.1 helicase RepA family protein -
NBC2815_RS10440 2290420..2290653 - 234 WP_002805742.1 hypothetical protein -
NBC2815_RS10445 2290735..2291739 + 1005 WP_002805744.1 hypothetical protein -
NBC2815_RS10450 2291861..2292118 + 258 WP_088061406.1 AlpA family phage regulatory protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14879.07 Da        Isoelectric Point: 5.1890

>T293560 WP_002805728.1 NZ_LT853880:c2287431-2287012 [Xanthomonas fragariae]
MIVLDTNVVSEAIKPEPNPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFGERVLMFDTE
AARHYAELAVKARTAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHQ

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9522.89 Da        Isoelectric Point: 5.7425

>AT293560 WP_002805732.1 NZ_LT853880:c2287682-2287428 [Xanthomonas fragariae]
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSEKRIRMGDALAELGRQVVLTNDDFAVLDQVRDKVPAEP
MRFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6H9H7

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6HLT7

References