293559

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 243259..243625 Replicon chromosome
Accession NZ_LT853880
Organism Xanthomonas fragariae strain NBC2815

Toxin (Protein)


Gene name EcnB Uniprot ID A0A1Y6HEL5
Locus tag NBC2815_RS01045 Protein ID WP_002809516.1
Coordinates 243259..243393 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1Y6GQE1
Locus tag NBC2815_RS01050 Protein ID WP_002809518.1
Coordinates 243473..243625 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBC2815_RS01020 238789..239393 - 605 Protein_191 drug/metabolite exporter YedA -
NBC2815_RS01025 239581..240379 + 799 WP_087946428.1 IS5 family transposase -
NBC2815_RS01030 240406..240606 - 201 Protein_193 peptidase M20 -
NBC2815_RS01035 240789..242078 - 1290 WP_002809514.1 tryptophan--tRNA ligase -
NBC2815_RS01040 242727..242728 - 2 WP_087946428.1 IS5 family transposase -
NBC2815_RS01045 243259..243393 - 135 WP_002809516.1 entericidin A/B family lipoprotein Toxin
NBC2815_RS01050 243473..243625 - 153 WP_002809518.1 entericidin A/B family lipoprotein Antitoxin
NBC2815_RS01055 243734..244657 - 924 WP_088060874.1 arginase -
NBC2815_RS01060 245015..245408 + 394 Protein_199 roadblock/LC7 domain-containing protein -
NBC2815_RS01065 245431..245661 + 231 Protein_200 GTPase -
NBC2815_RS01070 247203..247204 - 2 WP_088060875.1 IS5 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 232928..249006 16078


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4425.27 Da        Isoelectric Point: 10.2040

>T293559 WP_002809516.1 NZ_LT853880:c243393-243259 [Xanthomonas fragariae]
MKRAIVLLVLSVLSVGILSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5241.20 Da        Isoelectric Point: 9.4952

>AT293559 WP_002809518.1 NZ_LT853880:c243625-243473 [Xanthomonas fragariae]
MKRLLTLMVLGLFSAGVMTGCNTFAGAGKDMQRAGSKVEKKADNCSDGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A1Y6HEL5


Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6GQE1

References