Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2009200..2009471 Replicon chromosome
Accession NZ_LT838200
Organism Escherichia coli isolate WI2 isolate

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2009330..2009433 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2009200..2009471 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSZ51_RS10245 2005755..2006417 - 663 WP_000944256.1 exodeoxyribonuclease X -
DSZ51_RS10250 2006441..2007097 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
DSZ51_RS10255 2007199..2007429 - 231 WP_000916763.1 DNA polymerase III subunit theta -
DSZ51_RS10260 2007568..2007942 + 375 WP_000168747.1 CopC domain-containing protein YobA -
DSZ51_RS10265 2007946..2008818 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
DSZ51_RS10270 2008831..2009172 + 342 WP_000976476.1 YebY family protein -
- 2009200..2009471 - 272 - - Antitoxin
- 2009330..2009433 + 104 - - Toxin
DSZ51_RS10275 2009568..2010224 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
DSZ51_RS10280 2010225..2010416 - 192 WP_000457842.1 YebW family protein -
DSZ51_RS10285 2010521..2010757 - 237 WP_001295499.1 DUF1480 family protein -
DSZ51_RS10290 2010875..2012314 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T293540 NZ_LT838200:2009330-2009433 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT293540 NZ_LT838200:c2009471-2009200 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References