Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2009192..2009463 Replicon chromosome
Accession NZ_LT838196
Organism Escherichia coli isolate WI1 isolate

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2009322..2009425 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2009192..2009463 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WI2_RS10210 2005747..2006409 - 663 WP_000944256.1 exodeoxyribonuclease X -
WI2_RS10215 2006433..2007089 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
WI2_RS10220 2007191..2007421 - 231 WP_000916763.1 DNA polymerase III subunit theta -
WI2_RS10225 2007560..2007934 + 375 WP_000168747.1 CopC domain-containing protein YobA -
WI2_RS10230 2007938..2008810 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
WI2_RS10235 2008823..2009164 + 342 WP_000976476.1 YebY family protein -
- 2009192..2009463 - 272 - - Antitoxin
- 2009322..2009425 + 104 - - Toxin
WI2_RS10240 2009560..2010216 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
WI2_RS10245 2010217..2010408 - 192 WP_000457842.1 YebW family protein -
WI2_RS10250 2010513..2010749 - 237 WP_001295499.1 DUF1480 family protein -
WI2_RS10255 2010867..2012306 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T293515 NZ_LT838196:2009322-2009425 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT293515 NZ_LT838196:c2009463-2009192 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References