Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1981253..1981521 Replicon chromosome
Accession NZ_LT827011
Organism Escherichia coli O127:H6 isolate EPEC E2348/69 variety

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1981291..1981393 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1981253..1981521 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BQ9544_RS10725 1978410..1979849 + 1440 WP_001339709.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BQ9544_RS10730 1979967..1980203 + 237 WP_001295499.1 DUF1480 family protein -
BQ9544_RS10735 1980308..1980499 + 192 WP_001296140.1 YebW family protein -
BQ9544_RS10740 1980500..1981156 - 657 WP_000812706.1 protein-serine/threonine phosphatase -
- 1981253..1981521 + 269 - - Antitoxin
- 1981291..1981393 - 103 - - Toxin
BQ9544_RS10745 1981551..1981892 - 342 WP_000976470.1 YebY family protein -
BQ9544_RS10750 1981905..1982777 - 873 WP_000879263.1 copper homeostasis membrane protein CopD -
BQ9544_RS10755 1982781..1983155 - 375 WP_000204700.1 CopC domain-containing protein YobA -
BQ9544_RS10760 1983294..1983524 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BQ9544_RS10765 1983626..1984282 + 657 WP_000011646.1 carbon-nitrogen hydrolase family protein -
BQ9544_RS10770 1984306..1984968 + 663 WP_000944249.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T293496 NZ_LT827011:c1981393-1981291 [Escherichia coli O127:H6]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT293496 NZ_LT827011:1981253-1981521 [Escherichia coli O127:H6]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGGGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References